Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 10/20 | 0.43 |
| ▸ | CTSS | P25774 | 6/20 | 0.43 |
| ▸ | CTSK | P43235 | 5/20 | 0.43 |
| ▸ | CTSB | P07858 | 5/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL158021 | 0.83 | GAA (0.41) | GAA | |
| SCHEMBL2863808 | 0.80 | GAA (0.61) | CTSLCTSSCTSKCTSBNAMPT | |
| SCHEMBL1490709 | 0.80 | L3MBTL1 (0.55) | GAA | |
| SCHEMBL3313893 | 0.79 | GAA (0.41) | GAA | |
| SCHEMBL2156507 | 0.79 | NAMPT (0.47) | CTSLCTSSCTSKCTSBNAMPT | |
| SCHEMBL159472 | 0.79 | KMT2A (0.63) | GAA | |
| SCHEMBL1415854 | 0.78 | POLB (0.46) | GAA | |
| SCHEMBL1416098 | 0.78 | HPGD (0.59) | — | |
| SCHEMBL4318844 | 0.78 | SMN1; SMN2 (0.64) | GAA | |
| SCHEMBL8961219 | 0.77 | HDAC3 (0.32) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |