Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | CTSL | P07711 | 9/20 | 0.60 |
| ▸ | CTSS | P25774 | 7/20 | 0.60 |
| ▸ | CTSB | P07858 | 6/20 | 0.60 |
| ▸ | CTSK | P43235 | 5/20 | 0.60 |
| ▸ | NAMPT | P43490 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NAAA | Q02083 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31474545 | 0.82 | EPHX2 (0.50) | CTSLCTSSCTSBCTSKNAMPT | |
| SCHEMBL10451394 | 0.82 | LMNA (0.58) | GAACTSLCTSSCTSBCTSK | |
| SCHEMBL2156507 | 0.82 | NAMPT (0.47) | CTSLCTSSCTSBCTSKNAMPT | |
| SCHEMBL237683 | 0.82 | GAA (0.63) | GAALMNAPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL5517758 | 0.81 | CTSK (0.61) | CTSLCTSSCTSBCTSKSMN1; SMN2 | |
| SCHEMBL6447899 | 0.81 | CTSL (0.54) | CTSLCTSSCTSBCTSKSMN1; SMN2 | |
| SCHEMBL5525754 | 0.81 | HDAC6 (0.65) | GAANAAA | |
| SCHEMBL3455667 | 0.81 | GAA (0.57) | GAACTSLCTSBCTSKLMNA | |
| SCHEMBL9827345 | 0.81 | CTSL (0.61) | CTSLCTSSCTSBCTSKNAMPT | |
| SCHEMBL2686091 | 0.81 | CYP1A2 (0.55) | GAAALDH1A1SMN1; SMN2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3030561-A1 | N-CYANOMETHYLAMIDES AS INHIBITORS OF JANUS KINASE | Cadila Healthcare Limited (IN) | 2016-06-15 | — | — | EP | claimed |
| EP-3023422-A1 | PHENYL AMINO PYRIMIDINE COMPOUNDS AND USES THEREOF | YM BioSciences Australia Pty Ltd (AU) | 2016-05-25 | — | — | EP | claimed |
| WO-2015019365-A1 | N-CYANOMETHYLAMIDES AS INHIBITORS OF JANUS KINASE | CADILA HEALTHCARE LIMITED (IN) | 2015-02-12 | — | — | WO | claimed |
| EP-2152701-A1 | PHENYL AMINO PYRIMIDINE COMPOUNDS AND USES THEREOF | Cytopia Research Pty Ltd (AU) | 2010-02-17 | — | — | EP | claimed |
| WO-2008109943-A1 | PHENYL AMINO PYRIMIDINE COMPOUNDS AND USES THEREOF | CYTOPIA RESEARCH PTY LTD (AU) | 2008-09-18 | — | — | WO | claimed |
| EP-0210893-B1 | BENZAMIDES, PROCESS FOR THEIR PREPARATION AND THEIR THERAPEUTICAL USE | Laboratoires DELAGRANGE, Société Anonyme (FR) | 1990-10-03 | — | — | EP | claimed |
| EP-0210893-A1 | Benzamides, process for their preparation and their therapeutical use | Laboratoires DELAGRANGE, Société Anonyme (FR) | 1987-02-04 | — | — | EP | claimed |
| US-12570614-B2 | Phenyl amino pyrimidine compounds and uses thereof | GLAXOSMITH KLINE LLC (US) | 2026-03-10 | — | — | US | disclosed |
| US-12421213-B2 | Benzamides of pyrazolylamino- pyrimidinyl derivatives, and compositions and methods thereof | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2025-09-23 | — | — | US | disclosed |
| WO-2025106953-A1 | SUSTAINED DELIVERY OF NITRILE-CONTAINING JAK INHIBITORS FROM A HYDROGEL THROUGH REVERSIBLE THIOIMIDATE ADDUCTS | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2025-05-22 | — | — | WO | disclosed |
| US-20250115586-A1 | BENZAMIDES OF PYRAZOLYLAMINO- PYRIMIDINYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO LTD (CN) | 2025-04-10 | — | — | US | disclosed |
| CN-119118999-A | Benzamide derivatives of pyrazolyl-amino-pyrimidinyl and compositions and methods thereof | 凌科药业(杭州)有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-118955477-A | Benzamide derivatives of pyrazolyl-amino-pyrimidinyl and compositions and methods thereof | 凌科药业(杭州)有限公司 | 2024-11-15 | — | — | CN | disclosed |
| EP-0171768-A1 | Substituted propargyloxyacetonitrile derivatives, process for production thereof, and herbicide and agricultural-horticultural fungicide comprising said derivatives as active ingredients | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1986-02-19 | — | — | EP | disclosed |
| US-4552887-A | FUNGICIDES; PYRAZOLYL, TETRAZOLYL OR TRIAZOLYL GROUP | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-11-12 | — | — | US | disclosed |
| EP-0144177-A1 | Preparation of bromoacetamides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-06-12 | — | — | EP | disclosed |
| US-4515959-A | HERBICIDES, FUNGICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-05-07 | — | — | US | disclosed |
| US-4447446-A | PESTICIDE, HERBICIDE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-05-08 | — | — | US | disclosed |
| EP-0076030-A2 | Substituted amide derivatives, processes for preparing them, pesticidal compositions containing them and processes for combating unwanted vegetation and fungi | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-04-06 | — | — | EP | disclosed |
| EP-0059536-A2 | Amide derivatives, processes for preparing them, their use as fungicides and pesticidal compositions containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12570614-B2 | Phenyl amino pyrimidine compounds and uses thereof | JAK1, JAK2, JAK3 | GAA 4694/4885CTSL 4543/4885CTSS 4744/4885 |
| US-20250115586-A1 | BENZAMIDES OF PYRAZOLYLAMINO- PYRIMIDINYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | JAK1, JAK3, JAK2 | GAA 1068/4885CTSL 2477/4885CTSS 1878/4885 |
| US-12421213-B2 | Benzamides of pyrazolylamino- pyrimidinyl derivatives, and compositions and methods thereof | JAK2, JAK1, JAK3 | GAA 967/4885CTSL 3071/4885CTSS 2959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.