Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 12/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | GHSR | Q92847 | 3/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | LIPE | Q05469 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6957720 | 0.95 | SCN9A (0.35) | SCN9APABPC1JAK2JAK3PTK2 | |
| SCHEMBL6968593 | 0.94 | SCN9A (0.33) | SCN9APABPC1GHSRKDM4EALDH1A1 | |
| SCHEMBL6965676 | 0.91 | PABPC1 (0.41) | SCN9APABPC1P2RX7 | |
| SCHEMBL6965678 | 0.91 | PABPC1 (0.41) | SCN9APABPC1P2RX7 | |
| SCHEMBL6967090 | 0.89 | SCN9A (0.34) | SCN9APABPC1GHSRKDM4EALDH1A1 | |
| SCHEMBL6967088 | 0.89 | SCN9A (0.34) | SCN9APABPC1GHSRKDM4EALDH1A1 | |
| SCHEMBL6963186 | 0.89 | SCN9A (0.39) | SCN9APABPC1GHSRKDM4EALDH1A1 | |
| SCHEMBL6963190 | 0.89 | SCN9A (0.39) | SCN9APABPC1GHSRKDM4EALDH1A1 | |
| SCHEMBL6956720 | 0.89 | SCN9A (0.33) | SCN9APABPC1KDM4EALDH1A1GLA | |
| SCHEMBL6963911 | 0.89 | KLK7 (0.40) | SCN9APABPC1GHSRP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |