Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | NPR3 | P17342 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 4/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963186 | 1.00 | SCN9A (0.39) | SCN9AKDM4EALDH1A1GLAGAA | |
| SCHEMBL6961693 | 0.95 | SCN9A (0.38) | SCN9AKDM4EALDH1A1GLAGAA | |
| SCHEMBL6961689 | 0.95 | SCN9A (0.38) | SCN9AKDM4EALDH1A1GLAGAA | |
| SCHEMBL6967088 | 0.94 | SCN9A (0.34) | SCN9AKDM4EALDH1A1GLAGAA | |
| SCHEMBL6967090 | 0.94 | SCN9A (0.34) | SCN9AKDM4EALDH1A1GLAGAA | |
| SCHEMBL6968593 | 0.91 | SCN9A (0.33) | SCN9AKDM4EALDH1A1GLAGAA | |
| SCHEMBL6965676 | 0.90 | PABPC1 (0.41) | SCN9APABPC1NPR3 | |
| SCHEMBL6965678 | 0.90 | PABPC1 (0.41) | SCN9APABPC1NPR3 | |
| SCHEMBL6964322 | 0.90 | ALDH1A1 (0.40) | SCN9AKDM4EALDH1A1GLAGAA | |
| SCHEMBL6964320 | 0.90 | ALDH1A1 (0.40) | SCN9AKDM4EALDH1A1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6352993-B1 | ANTIULCER AGENTS | YUHAN CORPORATION (KR) | 2002-03-05 | — | — | US | disclosed |
| EP-1015444-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION, LTD. (KR) | 2000-07-05 | — | — | EP | disclosed |
| WO-1998043968-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 1998-10-08 | — | — | WO | disclosed |