Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | RBP4 | P02753 | 2/20 | 0.46 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | HTR1D | P28221 | 3/20 | 0.43 |
| ▸ | HTR1B | P28222 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963379 | 0.90 | RBP4 (0.46) | KMT2AL3MBTL1RBP4PANK3MAPT | |
| SCHEMBL6966645 | 0.86 | MAPT (0.60) | KMT2ARBP4MAPTRAB9AHTR1A | |
| SCHEMBL9058218 | 0.85 | PANK3 (0.62) | KMT2AL3MBTL1RBP4PANK3MAPT | |
| SCHEMBL8700515 | 0.84 | KDM4E (0.48) | KMT2AL3MBTL1RBP4PANK3MAPT | |
| SCHEMBL6962308 | 0.84 | RBP4 (0.56) | KMT2AL3MBTL1RBP4PANK3MAPT | |
| SCHEMBL8705827 | 0.84 | LMNA (0.61) | KMT2AL3MBTL1RBP4MAPTRAB9A | |
| SCHEMBL6966961 | 0.83 | RBP4 (0.46) | KMT2AL3MBTL1RBP4PANK3MAPT | |
| SCHEMBL8094380 | 0.83 | RBP4 (0.46) | KMT2AL3MBTL1RBP4PANK3MAPT | |
| SCHEMBL8699977 | 0.83 | MAPT (0.48) | KMT2AL3MBTL1RBP4PANK3MAPT | |
| SCHEMBL6652808 | 0.83 | RBP4 (0.57) | KMT2AL3MBTL1RBP4MAPTHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850222-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6028195-A | AN ANTITUMOR AGENT WITH VERY LOW TOXICITIES | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-02-22 | — | — | US | disclosed |