Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 4/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 5/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5203558 | 0.85 | VCP (0.47) | MAPK13MAPK9MAPK12MAPK11MAPK14 | |
| SCHEMBL5203241 | 0.84 | KDM1A (0.46) | MAPK13MAPK9MAPK12MAPK11MAPK14 | |
| SCHEMBL5206571 | 0.80 | VCP (0.43) | MAPK13MAPK9MAPK12MAPK11MAPK14 | |
| SCHEMBL311523 | 0.79 | MEN1 (0.62) | MAPK13MAPK9MAPK12MAPK11MAPK14 | |
| SCHEMBL5202721 | 0.79 | KDM1A (0.44) | KDM1AMAOBCSNK1A1CSNK1DRPS6KA3 | |
| SCHEMBL5202973 | 0.78 | VCP (0.45) | KDM1AMAOBMEN1POLBKMT2A | |
| SCHEMBL5205247 | 0.78 | VCP (0.45) | KDM1AMAOBMEN1POLBKMT2A | |
| SCHEMBL5206599 | 0.77 | GBA1 (0.48) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL14608992 | 0.77 | KCNH2 (0.47) | KDM1AMAOBMEN1POLBKMT2A | |
| SCHEMBL5206565 | 0.77 | KCNH2 (0.47) | KDM1AMAOBMEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1306085-A1 | 2-Cyclohexyl-4-phenyl-1H-imidazole derivatives as ligands for the neuropeptide Y5 receptor | Neurogen Corporation (US) | 2003-05-02 | — | — | EP | claimed |