Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7081212 | 0.94 | ALDH1A1 (0.34) | ALDH1A1GAAAPLNRTDP1TSHR | |
| SCHEMBL6968250 | 0.90 | ALDH1A1 (0.33) | ALDH1A1APLNRTDP1TSHR | |
| SCHEMBL6961583 | 0.89 | APLNR (0.31) | ALDH1A1APLNRTDP1TSHR | |
| SCHEMBL6971922 | 0.89 | TLR8 (0.32) | LMNATLR8 | |
| SCHEMBL6966228 | 0.89 | TLR8 (0.32) | LMNATLR8 | |
| SCHEMBL7083901 | 0.89 | ALDH1A1 (0.35) | ALDH1A1GAALMNAHTTAPLNR | |
| SCHEMBL7082117 | 0.88 | TLR8 (0.32) | LMNATLR8 | |
| SCHEMBL6972886 | 0.87 | TLR8 (0.33) | TLR8 | |
| SCHEMBL6960657 | 0.87 | HSP90B1 (0.33) | TLR8 | |
| SCHEMBL6973053 | 0.86 | HSP90B1 (0.38) | ALDH1A1MEN1KMT2ALMNATLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |