Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 11/20 | 0.76 |
| ▸ | PPARG | P37231 | 1/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970376 | 1.00 | AGTR1 (0.76) | AGTR1PPARGKCNH2 | |
| SCHEMBL6968791 | 0.99 | AGTR1 (0.76) | AGTR1PPARGKCNH2 | |
| SCHEMBL6963599 | 0.98 | AGTR1 (0.73) | AGTR1PPARGKCNH2 | |
| SCHEMBL6969979 | 0.93 | AGTR1 (0.67) | AGTR1PPARGKCNH2 | |
| SCHEMBL6977412 | 0.93 | AGTR1 (0.78) | AGTR1PPARGKCNH2 | |
| SCHEMBL7995129 | 0.92 | AGTR1 (0.65) | AGTR1PPARGKCNH2 | |
| SCHEMBL8124840 | 0.92 | AGTR1 (0.65) | AGTR1PPARGKCNH2 | |
| SCHEMBL7820631 | 0.92 | AGTR1 (0.64) | AGTR1PPARG | |
| SCHEMBL7818857 | 0.92 | AGTR1 (0.64) | AGTR1PPARG | |
| SCHEMBL7818624 | 0.92 | AGTR1 (0.64) | AGTR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991627-B1 | PYRIMIDINONE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE COMPOUNDS AND THE PROCESS FOR PREPARING THE SAME | BORYUNG PHARM (KR) | 2003-07-02 | — | — | EP | claimed |
| US-6294542-B1 | Pyrimidinone compounds, pharmaceutical compositions containing the compounds and the process for preparing the same | BORYUNG PHARMACEUTICAL CO. LTD. (KR) | 2001-09-25 | — | — | US | claimed |
| EP-0991627-A1 | PYRIMIDINONE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE COMPOUNDS AND THE PROCESS FOR PREPARING THE SAME | BORYUNG PHARMACEUTICAL CO., LTD. (KR) | 2000-04-12 | — | — | EP | claimed |
| WO-1999055681-A1 | PYRIMIDINONE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE COMPOUNDS AND THE PROCESS FOR PREPARING THE SAME | BORYUNG PHARMACEUTICAL CO., LTD. (KR) | 1999-11-04 | — | — | WO | claimed |
| EP-0991627-B1 | PYRIMIDINONE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE COMPOUNDS AND THE PROCESS FOR PREPARING THE SAME | BORYUNG PHARM (KR) | 2003-07-02 | — | — | EP | disclosed |