Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 11/20 | 0.67 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6977036 | 0.94 | AGTR1 (0.58) | AGTR1 | |
| SCHEMBL6968791 | 0.94 | AGTR1 (0.76) | AGTR1PPARGKCNH2 | |
| SCHEMBL6963599 | 0.94 | AGTR1 (0.73) | AGTR1PPARGKCNH2 | |
| SCHEMBL6970376 | 0.93 | AGTR1 (0.76) | AGTR1PPARGKCNH2 | |
| SCHEMBL6964233 | 0.93 | AGTR1 (0.76) | AGTR1PPARGKCNH2 | |
| SCHEMBL7818659 | 0.92 | AGTR1 (0.56) | AGTR1PPARG | |
| SCHEMBL6977412 | 0.92 | AGTR1 (0.78) | AGTR1PPARGKCNH2 | |
| SCHEMBL7811655 | 0.89 | AGTR1 (0.52) | AGTR1 | |
| SCHEMBL6964925 | 0.87 | AGTR1 (0.63) | AGTR1PPARG | |
| Fimasartan SCHEMBL2229436 | 0.86 | AGTR1 (0.75) | AGTR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991627-B1 | PYRIMIDINONE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE COMPOUNDS AND THE PROCESS FOR PREPARING THE SAME | BORYUNG PHARM (KR) | 2003-07-02 | — | — | EP | claimed |