Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | LAP3 | P28838 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | PLAT | P00750 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1745793 | 0.90 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1KMT2AMAPK1SLC6A2 | |
| SCHEMBL8804399 | 0.90 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1KMT2AMAPK1SLC6A2 | |
| SCHEMBL11472824 | 0.90 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1KMT2AMAPK1SLC6A2 | |
| Hydrochloric Acid SCHEMBL10886394 | 0.88 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1KMT2AMAPK1SLC6A2 | |
| Hydrochloric Acid SCHEMBL5552487 | 0.86 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1RAB9AKMT2AMAPK1 | |
| SCHEMBL31652735 | 0.86 | CNR2 (0.47) | CNR2ALDH1A1L3MBTL1KMT2AMAPK1 | |
| SCHEMBL29261445 | 0.86 | CNR2 (0.47) | CNR2ALDH1A1L3MBTL1KMT2AMAPK1 | |
| SCHEMBL5456496 | 0.86 | NR4A1 (0.53) | ALDH1A1L3MBTL1RAB9AKMT2AMAPT | |
| Hydrochloric Acid SCHEMBL31652655 | 0.84 | CNR2 (0.46) | CNR2ALDH1A1L3MBTL1KMT2AMAPK1 | |
| SCHEMBL10861854 | 0.84 | LTA4H (0.63) | L3MBTL1RAB9AMAPTMAOBSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11345715-B2 | Biologically active molecules, conjugates thereof, and therapeutic uses | REGENERON PHARMACEUTICALS, INC. (US) | 2022-05-31 | — | — | US | disclosed |
| US-20200277306-A1 | BIOLOGICALLY ACTIVE MOLECULES, CONJUGATES THEREOF, AND THERAPEUTIC USES | REGENERON PHARMACEUTICALS, INC. | 2020-09-03 | — | — | US | disclosed |
| US-10570151-B2 | Biologically active molecules, conjugates thereof, and therapeutic uses | REGENERON PHARMACEUTICALS, INC. (US) | 2020-02-25 | — | — | US | disclosed |
| US-20160030591-A1 | BIOLOGICALLY ACTIVE MOLECULES, CONJUGATES THEREOF, AND THERAPEUTIC USES | REGENERON PHARMACEUTICALS, INC. | 2016-02-04 | — | — | US | disclosed |
| EP-2968593-A1 | BIOLOGICALLY ACTIVE MOLECULES, CONJUGATES THEREOF, AND THERAPEUTIC USES | Regeneron Pharmaceuticals, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014145090-A1 | BIOLOGICALLY ACTIVE MOLECULES, CONJUGATES THEREOF, AND THERAPEUTIC USES | REGENERON PHARMACEUTICALS, INC. (US) | 2014-09-18 | — | — | WO | disclosed |
| EP-0713483-B1 | AMIDINE DERIVATIVES WITH NITRIC OXIDE SYNTHETASE ACTIVITIES | ASTRAZENECA AB (SE) | 2003-01-15 | — | — | EP | disclosed |
| US-6030985-A | Amidine derivatives with nitric oxide synthetase activities | ASTRA AKTIEBOLAG (SE) | 2000-02-29 | — | — | US | disclosed |
| US-5807885-A | Amidine derivatives with nitric oxide synthetase activities | ASTRA AKTIEBOLAG (SE) | 1998-09-15 | — | — | US | disclosed |
| EP-0713483-A1 | AMIDINE DERIVATIVES WITH NITRIC OXIDE SYNTHETASE ACTIVITIES | Astra Aktiebolag (SE) | 1996-05-29 | — | — | EP | disclosed |
| WO-1995005363-A1 | AMIDINE DERIVATIVES WITH NITRIC OXIDE SYNTHETASE ACTIVITIES | ASTRA AKTIEBOLAG (SE) | 1995-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10570151-B2 | Biologically active molecules, conjugates thereof, and therapeutic uses | CD47, CD44, ACP1 | CNR2 4095/4885ALDH1A1 934/4885L3MBTL1 1131/4885 |
| US-20160030591-A1 | BIOLOGICALLY ACTIVE MOLECULES, CONJUGATES THEREOF, AND THERAPEUTIC USES | CD47, CD44, ACP1 | CNR2 4095/4885ALDH1A1 934/4885L3MBTL1 1131/4885 |
| US-11345715-B2 | Biologically active molecules, conjugates thereof, and therapeutic uses | CD47, CD44, ACP1 | CNR2 4095/4885ALDH1A1 934/4885L3MBTL1 1131/4885 |
| US-20200277306-A1 | BIOLOGICALLY ACTIVE MOLECULES, CONJUGATES THEREOF, AND THERAPEUTIC USES | CD47, CD44, ACP1 | CNR2 4095/4885ALDH1A1 934/4885L3MBTL1 1131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.