Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960923 | 0.94 | ALDH1A1 (0.35) | ALDH1A1HPGDGSTP1TAAR1SMN1; SMN2 | |
| SCHEMBL472083 | 0.81 | ALDH1A1 (0.49) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL17373966 | 0.81 | ALDH1A1 (0.40) | ALDH1A1HPGDGSTP1TAAR1SMN1; SMN2 | |
| SCHEMBL8170012 | 0.81 | GSTP1 (0.46) | ALDH1A1HPGDGSTP1TAAR1SMN1; SMN2 | |
| SCHEMBL10548466 | 0.79 | ALDH1A1 (0.38) | ALDH1A1HPGDGSTP1TAAR1SMN1; SMN2 | |
| SCHEMBL472103 | 0.79 | ALDH1A1 (0.47) | ALDH1A1HPGDGSTP1SMN1; SMN2THRB | |
| SCHEMBL472109 | 0.78 | KMT2A (0.41) | ALDH1A1HPGDGSTP1TAAR1SMN1; SMN2 | |
| SCHEMBL6165925 | 0.78 | ALDH1A1 (0.45) | ALDH1A1HPGDTAAR1SMN1; SMN2NPC1 | |
| SCHEMBL28820040 | 0.77 | ALDH1A1 (0.46) | ALDH1A1HPGDGSTP1SMN1; SMN2THRB | |
| SCHEMBL3508185 | 0.77 | TSHR (0.45) | ALDH1A1HPGDGSTP1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |