Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL697006 | 0.91 | CTSS (0.62) | CTSSCTSL | |
| SCHEMBL8384085 | 0.91 | CTSS (0.62) | CTSSCTSL | |
| SCHEMBL13148523 | 0.91 | CTSS (0.62) | CTSSCTSL | |
| SCHEMBL695795 | 0.86 | CTSS (0.78) | CTSS | |
| SCHEMBL694322 | 0.85 | CTSS (0.77) | CTSS | |
| Hydrochloric Acid SCHEMBL695437 | 0.84 | CTSS (0.75) | CTSS | |
| SCHEMBL695956 | 0.83 | CTSS (1.00) | CTSSCTSL | |
| SCHEMBL696004 | 0.83 | CTSS (1.00) | CTSSCTSL | |
| SCHEMBL3070456 | 0.83 | CTSS (0.44) | CTSSCTSL | |
| Hydrochloric Acid SCHEMBL695373 | 0.82 | CTSS (0.98) | CTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163793-B2 | Proline derivatives | HOFFMAN-LA ROCHE INC. (US) | 2012-04-24 | — | — | US | disclosed |
| EP-2421826-A1 | PROLINE DERIVATIVES AS CATHEPSIN INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2012-02-29 | — | — | EP | disclosed |
| WO-2010121918-A1 | PROLINE DERIVATIVES AS CATHEPSIN INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-10-28 | — | — | WO | disclosed |