Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.53 |
| ▸ | PPARA | Q07869 | 9/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6959746 | 0.84 | FFAR1 (0.67) | PPARGPPARAFFAR1KDRMAPT | |
| SCHEMBL14281856 | 0.80 | PPARG (0.61) | PPARGPPARAFFAR1KDRMAPT | |
| SCHEMBL14302921 | 0.80 | PPARG (0.61) | PPARGPPARAFFAR1KDRMAPT | |
| SCHEMBL14307032 | 0.78 | PPARG (0.59) | PPARGPPARAFFAR1KDRMAPT | |
| SCHEMBL19392906 | 0.77 | FFAR1 (0.68) | PPARGPPARAFFAR1KDRMAPT | |
| SCHEMBL8123842 | 0.77 | KDR (0.52) | PPARGPPARAFFAR1KDRMAPT | |
| SCHEMBL9260070 | 0.77 | ALOX5 (0.61) | PPARGPPARAFFAR1KDRMAPT | |
| SCHEMBL8134271 | 0.77 | KDR (0.51) | PPARGPPARAFFAR1KDRMAPT | |
| SCHEMBL4030957 | 0.76 | FFAR1 (0.70) | PPARGPPARAFFAR1KDRMAPT | |
| SCHEMBL4032011 | 0.76 | FFAR1 (0.70) | PPARGPPARAFFAR1KDRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0629624-B1 | Tetrazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-5591862-A | ANTILIPEMICS, TREATING DIABETES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| EP-0629624-A1 | Tetrazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-21 | — | — | EP | disclosed |