Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 11/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7872790 | 0.76 | SMN1; SMN2 (0.49) | LIPESMN1; SMN2ALDH1A1HTTCCNA2 | |
| SCHEMBL7550336 | 0.69 | LIPE (1.00) | LIPESMN1; SMN2ALDH1A1HTT | |
| SCHEMBL2906873 | 0.68 | KMT2A (0.36) | SMN1; SMN2 | |
| SCHEMBL2901849 | 0.67 | — | — | |
| SCHEMBL3841963 | 0.67 | — | — | |
| SCHEMBL910451 | 0.66 | LIPE (0.53) | LIPESMN1; SMN2ALDH1A1HTTCYP2D6 | |
| SCHEMBL2907656 | 0.66 | — | — | |
| SCHEMBL10757188 | 0.65 | LIPE (0.73) | LIPESMN1; SMN2ALDH1A1 | |
| SCHEMBL28242343 | 0.64 | LIPE (0.50) | LIPESMN1; SMN2HTTCYP2D6 | |
| SCHEMBL7208112 | 0.63 | LIPE (0.50) | LIPESMN1; SMN2ALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1114038-B1 | ISOTHIAZOLE CARBOXYLIC ACID AMIDES | BAYER CROPSCIENCE AG (DE) | 2003-12-03 | — | — | EP | disclosed |
| EP-1114038-A1 | ISOTHIAZOLE CARBOXYLIC ACID AMIDES | Bayer Aktiengesellschaft (DE) | 2001-07-11 | — | — | EP | disclosed |
| WO-2000015622-A1 | ISOTHIAZOLE CARBOXYLIC ACID AMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-03-23 | — | — | WO | disclosed |