SCHEMBL2906873

SCHEMBL2906873

CCNC(=O)Oc1snc(Cl)c1Cl

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.36
MAPT P10636 3/20 0.34
MEN1 O00255 2/20 0.34
KDM4E B2RXH2 1/20 0.34
POLB P06746 1/20 0.34
GAA P10253 1/20 0.34
THRB P10828 1/20 0.34
BLM P54132 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
CHRM4 P08173 1/20 0.32
LMNA P02545 1/20 0.32
HPGD P15428 1/20 0.32
NFKB1 P19838 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MMP2 P08253 1/20 0.30
MMP9 P14780 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3841963 0.77
SCHEMBL2901849 0.73
SCHEMBL2907656 0.72
SCHEMBL3566444 0.71 LMNA (0.42) MAPTKDM4EGAAL3MBTL1NPC1
SCHEMBL6964599 0.68 LIPE (0.52) SMN1; SMN2
SCHEMBL11304010 0.65 KMT2A (0.37) KMT2AMAPTMEN1KDM4EPOLB
SCHEMBL23810117 0.65
SCHEMBL9952093 0.62 KDM4E (0.51) KMT2AMAPTMEN1KDM4EPOLB
SCHEMBL27601867 0.62 TAAR1 (0.58) KMT2ASMN1; SMN2MMP2MMP9MMP8
SCHEMBL7088428 0.61 ALDH1A1 (0.42) MAPTKDM4EGAANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1260140-B1 Isothiazolecarbamide derivatives for crop protection BAYER CROPSCIENCE AG (DE) 2010-08-18 EP disclosed
EP-2145540-A1 Isothiazol carboxylic acid amides and their use in the protection of plants Bayer CropScience AG (DE) 2010-01-20 EP disclosed
EP-2145539-A1 Isothiazolecarbamide derivatives for crop protection Bayer CropScience AG (DE) 2010-01-20 EP disclosed
EP-2132988-A1 Isothiazole carboxylic acid amides and their use in the protection of plants Bayer CropScience AG (DE) 2009-12-16 EP disclosed
EP-1049683-B1 ISOTHIAZOLE CARBOXYLIC ACID AMIDES AND THE APPLICATION THEREOF IN ORDER TO PROTECT PLANTS BAYER CROPSCIENCE AG (DE) 2003-06-18 EP disclosed
EP-1260140-A1 Isothiazolecarbamide derivatives for crop protection Bayer CropScience AG (DE) 2002-11-27 EP disclosed
EP-1049683-A2 ISOTHIAZOLE CARBOXYLIC ACID AMIDES AND THE APPLICATION THEREOF IN ORDER TO PROTECT PLANTS BAYER AG (DE) 2000-11-08 EP disclosed
WO-1999024413-A2 ISOTHIAZOLE CARBOXYLIC ACID AMIDES AND THE APPLICATION THEREOF IN ORDER TO PROTECT PLANTS BAYER AKTIENGESELLSCHAFT (DE) 1999-05-20 WO disclosed