Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6200485 | 0.77 | PARP1 (0.36) | PARP1 | |
| SCHEMBL6625356 | 0.69 | PARP1 (0.32) | PARP1 | |
| SCHEMBL64500 | 0.67 | PARP1 (0.45) | PARP1MCL1 | |
| SCHEMBL1395813 | 0.64 | MCL1 (0.44) | PARP1MCL1 | |
| SCHEMBL30955312 | 0.64 | MCL1 (0.44) | PARP1MCL1 | |
| SCHEMBL10647007 | 0.63 | L3MBTL1 (0.44) | CYP2A6SRD5A1POLB | |
| SCHEMBL4421682 | 0.63 | HTR1A (0.46) | MCL1POLB | |
| SCHEMBL2266482 | 0.63 | PARP1 (0.41) | PARP1SLC9A1MCL1 | |
| SCHEMBL12037714 | 0.62 | PARP1 (0.41) | ACHEPARP1SLC9A1MCL1 | |
| SCHEMBL6798145 | 0.62 | PARP1 (0.41) | ACHEPARP1SLC9A1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807631-B1 | Tricyclic compounds having fungicidal activity, their preparation and their use | SANKYO CO (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-5981752-A | Tricyclic compounds having fungicidal activity, their preparation and their use | SANKYO COMPANY, LIMITED (JP) | 1999-11-09 | — | — | US | disclosed |
| US-5773618-A | PYRROLOQUINOLINONE DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0807631-A1 | Tricyclic compounds having fungicidal activity, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1997-11-19 | — | — | EP | disclosed |
| US-4598156-A | Process for producing indoles unsubstituted in the 2,3-position and N(3-chloropropionyl)indole produced thereby | CIBA GEIGY CORPORATION (US) | 1986-07-01 | — | — | US | disclosed |