SCHEMBL696479

SCHEMBL696479

CCC(Cl)(Cl)OCC1CO1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.56
TSHR P16473 5/20 0.42
MAPK1 P28482 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
TDP1 Q9NUW8 3/20 0.38
TP53 P04637 3/20 0.34
MAPT P10636 2/20 0.34
HPGD P15428 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
HIF1A Q16665 2/20 0.34
CYP1A2 P05177 1/20 0.34
PPARG P37231 1/20 0.34
GLA P06280 1/20 0.32
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11418986 0.80 ALDH1A1 (0.52) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL7170116 0.77 ALDH1A1 (0.60) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL17090716 0.76 ALDH1A1 (0.64) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL1700016 0.76 ALDH1A1 (0.64) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL11744628 0.76 ALDH1A1 (0.64) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL11316599 0.74 ALDH1A1 (0.56) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL13893627 0.74 ALDH1A1 (0.56) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL7167454 0.74 ALDH1A1 (0.56) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL11319302 0.72 ALDH1A1 (0.59) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1
SCHEMBL18100542 0.72 ALDH1A1 (0.73) ALDH1A1TSHRMAPK1SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9605350-B2 Process and apparatus for purification of industrial brine BLUE CUBE IP LLC (US) 2017-03-28 US disclosed
EP-2565159-B1 Process and apparatus for purification of industrial brine DOW GLOBAL TECHNOLOGIES LLC (US) 2015-07-08 EP disclosed
US-20130281721-A1 PROCESS AND APPARATUS FOR PURIFICATION OF INDUSTRIAL BRINE BLUE CUBE IP LLC 2013-10-24 US disclosed
EP-2183188-B1 PROCESS AND APPARATUS FOR PURIFICATION OF INDUSTRIAL BRINE DOW GLOBAL TECHNOLOGIES LLC (US) 2013-10-23 EP disclosed
US-8501034-B2 Process and apparatus for purification of industrial brine DOW GLOBAL TECHNOLOGIES LLC (US) 2013-08-06 US disclosed
EP-2567941-A1 Brine purification Dow Global Technologies LLC (US) 2013-03-13 EP disclosed
EP-2565159-A1 Process and apparatus for purification of industrial brine Dow Global Technologies LLC (US) 2013-03-06 EP disclosed
US-8343328-B2 Brine purification DOW GLOBAL TECHNOLOGIES LLC (US) 2013-01-01 US disclosed
EP-2423165-A1 Process, adapted microbes, composition and apparatus for purification of industrial brine Dow Global Technologies LLC (US) 2012-02-29 EP disclosed
US-20100261255-A1 PROCESS, ADAPTED MICROBES, COMPOSITION AND APPARATUS FOR PURIFICATION OF INDUSTRIAL BRINE DOW GLOBAL TECHNOLOGIES LLC 2010-10-14 US disclosed
US-20100219372-A1 BRINE PURIFICATION DOW GLOBAL TECHNOLOGIES LLC 2010-09-02 US disclosed
US-20100193732-A1 PROCESS AND APPARATUS FOR PURIFICATION OF INDUSTRIAL BRINE BLUE CUBE IP LLC 2010-08-05 US disclosed
EP-2183187-A2 BRINE PURIFICATION Dow Global Technologies Inc. (US) 2010-05-12 EP disclosed
EP-2183189-A2 PROCESS, ADAPTED MICROBES, COMPOSITION AND APPARATUS FOR PURIFICATION OF INDUSTRIAL BRINE Dow Global Technologies Inc. (US) 2010-05-12 EP disclosed
EP-2183188-A1 PROCESS AND APPARATUS FOR PURIFICATION OF INDUSTRIAL BRINE Dow Global Technologies Inc. (US) 2010-05-12 EP disclosed
WO-2009026208-A2 BRINE PURIFICATION DOW GLOBAL TECHNOLOGIES INC. (US) 2009-02-26 WO disclosed
WO-2009026211-A2 PROCESS, ADAPTED MICROBES, COMPOSITION AND APPARATUS FOR PURIFICATION OF INDUSTRIAL BRINE DOW GLOBAL TECHNOLOGIES INC. (US) 2009-02-26 WO disclosed
WO-2009026210-A1 PROCESS AND APPARATUS FOR PURIFICATION OF INDUSTRIAL BRINE DOW GLOBAL TECHNOLOGIES INC. (US) 2009-02-26 WO disclosed