Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.50 |
| ▸ | OXER1 | Q8TDS5 | 4/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | RXRA | P19793 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.46 |
| ▸ | F7 | P08709 | 3/20 | 0.46 |
| ▸ | F3 | P13726 | 3/20 | 0.46 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL696492 | 1.00 | ALDH1A1 (0.50) | ALDH1A1CYP19A1OXER1PPARGMAPT | |
| Acetic Acid SCHEMBL7533517 | 1.00 | ALDH1A1 (0.50) | ALDH1A1CYP19A1OXER1PPARGMAPT | |
| Bicarbonate SCHEMBL702474 | 0.89 | ALDH1A1 (0.52) | ALDH1A1CYP19A1OXER1PPARGMAPT | |
| Bicarbonate SCHEMBL9579037 | 0.89 | ALDH1A1 (0.52) | ALDH1A1CYP19A1OXER1PPARGMAPT | |
| Acetic Acid SCHEMBL17459602 | 0.86 | ALDH1A1 (0.63) | ALDH1A1CYP19A1OXER1PPARGMAPT | |
| Acetic Acid SCHEMBL28309147 | 0.86 | ALDH1A1 (0.41) | ALDH1A1CYP19A1OXER1PPARGMAPT | |
| Acetic Acid SCHEMBL28254877 | 0.84 | — | — | |
| Acetic Acid SCHEMBL11748243 | 0.84 | — | — | |
| Cis-3-Hexenol SCHEMBL245795 | 0.84 | ALDH1A1 (0.50) | ALDH1A1CYP19A1OXER1PPARGMAPT | |
| Acetic Acid SCHEMBL28963568 | 0.84 | ALDH1A1 (0.50) | ALDH1A1CYP19A1OXER1PPARGMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105532661-B | A kind of induction insect resistant agent preventing and treating tea tree looper class pest | 中国农业科学院茶叶研究所 | 2018-11-20 | — | — | CN | claimed |
| CN-105145515-B | A kind of utilization volatile matter attractant preventing and treating and the method for monitoring tea geometrid | 中国农业科学院茶叶研究所 | 2017-08-22 | — | — | CN | claimed |
| CN-105052927-B | A kind of tea geometrid male imago attractant based on tea plant volatiles | 中国农业科学院茶叶研究所 | 2017-08-22 | — | — | CN | claimed |
| CN-102165962-B | Natural enemy attractant for controlling population quantity of rice planthoppers | UNIV ZHEJIANG | 2013-06-05 | — | — | CN | claimed |
| CN-102165962-A | Natural enemy attractant for controlling population quantity of rice planthoppers | UNIV ZHEJIANG | 2011-08-31 | — | — | CN | claimed |
| CN-102144638-A | Anagrus nilaparvatae attractant | UNIV ZHEJIANG | 2011-08-10 | — | — | CN | claimed |
| CN-105532661-B | A kind of induction insect resistant agent preventing and treating tea tree looper class pest | 中国农业科学院茶叶研究所 | 2018-11-20 | — | — | CN | disclosed |
| CN-207476743-U | A kind of light combines the device of trapping tea lesser leafhopper with chemical information | 江苏省农业科学院 | 2018-06-12 | — | — | CN | disclosed |
| CN-104542528-B | Anoplophora glabripennis visual effect modified intercepts baffle-type trapper | 东北林业大学 | 2018-04-13 | — | — | CN | disclosed |
| CN-107406801-A | Reappear the flavor compositions of fig fragrance | 愛茉莉太平洋股份有限公司 | 2017-11-28 | — | — | CN | disclosed |
| CN-105145515-B | A kind of utilization volatile matter attractant preventing and treating and the method for monitoring tea geometrid | 中国农业科学院茶叶研究所 | 2017-08-22 | — | — | CN | disclosed |
| CN-105052927-B | A kind of tea geometrid male imago attractant based on tea plant volatiles | 中国农业科学院茶叶研究所 | 2017-08-22 | — | — | CN | disclosed |
| CN-102144638-B | Anagrus nilaparvatae attractant | UNIV ZHEJIANG | 2013-06-05 | — | — | CN | disclosed |
| EP-2421815-B1 | ACETALS AS PERFUMING INGREDIENTS | FIRMENICH & CIE (CH) | 2013-05-01 | — | — | EP | disclosed |
| US-8236749-B2 | Acetals as perfuming ingredients | FIRMENICH SA (CH) | 2012-08-07 | — | — | US | disclosed |
| EP-2421815-A1 | ACETALS AS PERFUMING INGREDIENTS | Firmenich S.A. (CH) | 2012-02-29 | — | — | EP | disclosed |
| US-20120010114-A1 | ACETALS AS PERFUMING INGREDIENTS | FIRMENICH SA (CH) | 2012-01-12 | — | — | US | disclosed |
| CN-102165962-A | Natural enemy attractant for controlling population quantity of rice planthoppers | UNIV ZHEJIANG | 2011-08-31 | — | — | CN | disclosed |
| CN-102144638-A | Anagrus nilaparvatae attractant | UNIV ZHEJIANG | 2011-08-10 | — | — | CN | disclosed |
| WO-2010122451-A1 | ACETALS AS PERFUMING INGREDIENTS | FIRMENICH SA (CH) | 2010-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010114-A1 | ACETALS AS PERFUMING INGREDIENTS | CBR1, CBR3, C9 | ALDH1A1 131/4885CYP19A1 501/4885OXER1 167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.