Cis-3-Hexenol

Cis-3-Hexenol

SCHEMBL245795

CC(=O)O.CCC=CCCO

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Cis-3-Hexenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.50
CYP19A1 P11511 4/20 0.50
PPARG P37231 3/20 0.50
OXER1 Q8TDS5 3/20 0.50
MAPT P10636 3/20 0.50
RXRA P19793 2/20 0.50
FFAR1 O14842 2/20 0.50
PTGS1 P23219 4/20 0.47
F7 P08709 3/20 0.47
F3 P13726 3/20 0.47
PPARA Q07869 3/20 0.47
KMT2A Q03164 2/20 0.47
PPARD Q03181 2/20 0.47
ADORA3 P0DMS8 1/20 0.47
CNR1 P21554 2/20 0.44
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
NR1I2 O75469 1/20 0.44
LMNA P02545 1/20 0.44
PLA2G1B P04054 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cis-3-Hexenol SCHEMBL28740459 1.00 ALDH1A1 (0.50) ALDH1A1CYP19A1PPARGOXER1MAPT
Cis-3-Hexenol SCHEMBL28042280 1.00 ALDH1A1 (0.50) ALDH1A1CYP19A1PPARGOXER1MAPT
Acetic Acid SCHEMBL18339443 0.93 ALDH1A1 (0.61) ALDH1A1CYP19A1PPARGOXER1MAPT
Acetic Acid SCHEMBL20721902 0.93 ALDH1A1 (0.61) ALDH1A1CYP19A1PPARGOXER1MAPT
Cis-3-Hexenol SCHEMBL7952091 0.88 ALDH1A1 (0.48) ALDH1A1CYP19A1PPARGOXER1MAPT
Cis-3-Hexenol SCHEMBL28510274 0.88 ALDH1A1 (0.54) ALDH1A1CYP19A1PPARGOXER1MAPT
Cis-3-Hexenol SCHEMBL309687 0.87
Cis-3-Hexenol SCHEMBL112920 0.87
Cis-3-Hexenol SCHEMBL1448560 0.87 ALDH1A1 (0.42) ALDH1A1CYP19A1PPARGOXER1MAPT
Cis-3-Hexenol SCHEMBL96295 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 405 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024175295-A1 DETERGENTS AND CLEANING AGENTS COMPRISING DISPERSIN AND FRAGRANCE HENKEL AG & CO. KGAA (DE) 2024-08-29 WO claimed
CN-115769818-B Application of (cis) -3-hexenol acetate in inducing spodoptera frugiperda to spawn and serve as spodoptera frugiperda attractant 华南农业大学 2023-05-12 CN claimed
CN-115769818-A Application of (cis) -3-hexenol acetate in inducing spodoptera frugiperda to lay eggs and serving as spodoptera frugiperda attractant 华南农业大学 2023-03-10 CN claimed
CN-102511493-B Liriomyza sativae attractant HANGZHOU ZHIBAO CLAY FERTILIZER STATION 2014-06-18 CN claimed
CN-106459939-B Lipase variants and polynucleotides encoding same 诺维信公司 2026-05-22 CN disclosed
US-20260132388-A1 LIPASE VARIANTS AND MICROCAPSULE COMPOSITIONS COMPRISING SUCH LIPASE VARIANTS NOVOZYMES A/S (DK) 2026-05-14 US disclosed
EP-4717756-A2 LIPASE VARIANTS AND DETERGENT COMPOSITIONS Novozymes A/S (DK) 2026-04-01 EP disclosed
US-12559736-B2 Lipase variants and polynucleotides encoding same NOVOZYMES A/S (DK) 2026-02-24 US disclosed
US-12529017-B2 Detergent composition comprising a lipase NOVOZYMES A/S (DK) 2026-01-20 US disclosed
US-20250382594-A1 METHODS OF REDUCING ODOR NOVOZYMES A/S (DK) 2025-12-18 US disclosed
US-12492387-B2 Lipase variants and microcapsule compositions comprising such lipase variants NOVOZYMES A/S (DK) 2025-12-09 US disclosed
US-20250368924-A1 LIPASE VARIANTS AND COMPOSITIONS COMPRISING SUCH LIPASE VARIANTS NOVOZYMES A/S (DK) 2025-12-04 US disclosed
EP-1342775-B1 Hetero spiro compound as perfuming and flavoring ingredient FIRMENICH & CIE (CH) 2005-08-24 EP disclosed
US-20050140032-A1 Device for dispensing active volatile liquid FIRMENICH SA (CH) 2005-06-30 US disclosed
EP-1467959-A1 ACETALS OF 2,4,7-DECATRIENAL AS PERFUMING OR FLAVORING INGREDIENTS FIRMENICH SA (CH) 2004-10-20 EP disclosed
EP-1342775-A1 Hetero spiro compound as perfuming and flavoring ingredient FIRMENICH SA (CH) 2003-09-10 EP disclosed
WO-2003062183-A1 ACETALS OF 2,4,7-DECATRIENAL AS PERFUMING OR FLAVORING INGREDIENTS FIRMENICH SA (CH) 2003-07-31 WO disclosed
EP-1329497-A2 Utilization of unsaturated esters as perfuming ingredients FIRMENICH SA (CH) 2003-07-23 EP disclosed
EP-0955290-B1 Unsaturated ketones and their use in perfumery FIRMENICH & CIE (CH) 2003-03-19 EP disclosed
US-6177400-B1 IMPROVING OR MODIFYING THE ODOR OF A PERFUME BY ADDING 4,6,6-TRIMETHYL-1,(3)-CYCLOHEX(ADI)ENE 1-SUBSTITUTED WITH ESTERS, ETHERS OR KETONES, SUCH AS (E)-1-(4,6,6-TRIMETHYL-1,3-CYCLOHEXADIEN-1-YL)-2-BUTEN-1-ONE FIRMENICH SA (CH) 2001-01-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559736-B2 Lipase variants and polynucleotides encoding same LPL, PNLIP, LIPG ALDH1A1 3681/4885CYP19A1 3000/4885PPARG 3690/4885
US-20260132388-A1 LIPASE VARIANTS AND MICROCAPSULE COMPOSITIONS COMPRISING SUCH LIPASE VARIANTS LIPE, LPL, PNLIP ALDH1A1 3173/4885CYP19A1 1002/4885PPARG 2458/4885
US-12529017-B2 Detergent composition comprising a lipase MGLL, LPL, LIPC ALDH1A1 2525/4885CYP19A1 1483/4885PPARG 1602/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.