Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965396 | 0.93 | CES2 (0.36) | CES2TSHRZDHHC20TDP1 | |
| SCHEMBL6969895 | 0.86 | — | — | |
| SCHEMBL6964938 | 0.84 | TSHR (0.35) | CES2TSHRMEN1KMT2ASLC1A2 | |
| SCHEMBL6971619 | 0.79 | TSHR (0.37) | CES2TSHRTDP1MEN1KMT2A | |
| SCHEMBL6965399 | 0.78 | EPHX2 (0.37) | CES2TSHRMEN1KMT2ASLC1A2 | |
| SCHEMBL11771559 | 0.77 | TSHR (0.45) | TSHRTDP1ALDH1A1 | |
| SCHEMBL22492321 | 0.77 | KMT2A (0.43) | CES2TSHRTDP1MEN1KMT2A | |
| SCHEMBL22227387 | 0.75 | TSHR (0.43) | TSHRTDP1ALDH1A1 | |
| SCHEMBL1727035 | 0.75 | TSHR (0.43) | TSHRTDP1ALDH1A1 | |
| SCHEMBL6965605 | 0.74 | CES2 (0.36) | CES2TSHRZDHHC20TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |