Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 5/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971619 | 0.94 | TSHR (0.37) | CES2TSHRTDP1PDE3BPDE3A | |
| SCHEMBL11477276 | 0.86 | TSHR (0.37) | TSHRTDP1HSD17B10MGAMGAA | |
| SCHEMBL6965396 | 0.80 | CES2 (0.36) | CES2TSHRTDP1PDE3BPDE3A | |
| SCHEMBL6965399 | 0.79 | EPHX2 (0.37) | CES2TSHRMEN1KMT2A | |
| SCHEMBL22492321 | 0.76 | KMT2A (0.43) | CES2TSHRTDP1MGAMGAA | |
| SCHEMBL444990 | 0.76 | TSHR (0.58) | TSHRMEN1KMT2A | |
| SCHEMBL1038709 | 0.76 | GAA (0.44) | CES2TSHRHSD17B10MGAMGAA | |
| SCHEMBL7051236 | 0.76 | CES2 (0.61) | CES2TSHRMEN1KMT2A | |
| SCHEMBL25277310 | 0.76 | TSHR (0.37) | CES2TSHRHSD17B10MGAMGAA | |
| SCHEMBL11794531 | 0.75 | TSHR (0.47) | TSHRGAAZDHHC20KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |