SCHEMBL992038

SCHEMBL992038

O=C(Cl)Nc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.64
TP53 P04637 1/20 0.64
EPHX1 P07099 1/20 0.64
TSHR P16473 1/20 0.64
CDK9 P50750 1/20 0.64
SMN1; SMN2 Q16637 1/20 0.64
CLK4 Q9HAZ1 1/20 0.64
POLB P06746 2/20 0.59
NAPRT Q6XQN6 1/20 0.58
HSD17B10 Q99714 1/20 0.58
CASP3 P42574 1/20 0.54
SENP7 Q9BQF6 1/20 0.54
GAA P10253 3/20 0.53
RAB9A P51151 2/20 0.53
ATM Q13315 2/20 0.53
NPC1 O15118 1/20 0.53
HSP90AA1 P07900 1/20 0.53
MAOA P21397 1/20 0.52
MAOB P27338 1/20 0.52
TGM2 P21980 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7525873 0.86 PTPN1 (0.64) SMN1; SMN2RAB9ANPC1MAPTMEN1
SCHEMBL11154886 0.86 NPC1 (0.48) EPHX2TP53EPHX1TSHRCDK9
SCHEMBL11161409 0.82 GPR35 (0.58) POLBHSD17B10RAB9ANPC1MAPT
SCHEMBL11717660 0.82 SMN1; SMN2 (0.61) EPHX2TP53EPHX1TSHRCDK9
SCHEMBL13926150 0.81 SMN1; SMN2 (0.67) EPHX2TP53EPHX1TSHRCDK9
SCHEMBL6964944 0.80 SMN1; SMN2 (0.58) EPHX2TP53EPHX1TSHRCDK9
SCHEMBL5580396 0.80 SMN1; SMN2 (0.58) EPHX2TP53EPHX1TSHRCDK9
Acetanilide SCHEMBL28024825 0.78 NAPRT (0.86) EPHX2TP53EPHX1TSHRCDK9
SCHEMBL7634 0.78 EPHX2 (0.70) EPHX2TP53EPHX1TSHRCDK9
Diphenylurea SCHEMBL133103 0.78 SMN1; SMN2 (1.00) EPHX2TP53EPHX1TSHRCDK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 278 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3181548-B1 PRODUCTION OF DI- AND POLYISOCYANATES OF THE DIPHENYLMETHANE SERIES HAVING A DEFINED CONTENT OF HYDROLYSABLE CHLORINE COVESTRO DEUTSCHLAND AG (DE) 2020-10-21 EP claimed
CN-101066937-A Synthesis process of N-chloromethyl-N-phenyl amino formyl chloride JIANG YIQING (CN) 2007-11-07 CN claimed
EP-0726248-B1 Process for the preparation of anilides of O-acyloxycarboxylic acids CLARIANT GMBH (DE) 1998-04-15 EP claimed
US-5693852-A REACTING IN SOLUTION A CHLOROCARBOXANILIDE WITH AN ALKALI METAL CARBOXYLATE AND A CARBOXYLIC ACID; EFFICIENCY; POLLUTION CONTROL HOECHST AKTIENGESELLSCHAFT (DE) 1997-12-02 US claimed
EP-0142670-A2 A process for the preparation of known herbicidally active phenyl carbamates BEROL NOBEL (SUISSE) S.A. (CH) 1985-05-29 EP claimed
WO-1985001286-A1 A PROCESS FOR THE PREPARATION OF HERBICIDALLY ACTIVE PHENYL CARBAMATES AND HERBICIDAL COMPOSITIONS CONTAINING THE SAME KEMISK VA^ERK KO^/GE A/S (DK) 1985-03-28 WO claimed
EP-0015567-B1 PROCESS FOR PREPARATION OF PHENYLCARBAMIC ACID CHLORIDES BASF Aktiengesellschaft (DE) 1982-12-15 EP claimed
US-4328165-A PHOSGENATION BASF AKTIENGESELLSCHAFT (DE) 1982-05-04 US claimed
US-4317752-A POLYURETHANE FOAMS; INSULATION; CONSTRUCTION MATERIALS BLOUNT DAVID H 1982-03-02 US claimed
US-4280006-A Process for the production of polyisocyanate silicate plastics utilizing an alkali metal cellulose silicate condensation product BLOUNT DAVID H 1981-07-21 US claimed
US-4262108-A FIREPROOF CONSTRUCTION MATERIALS, INSULATION BLOUNT DAVID H 1981-04-14 US claimed
US-4153764-A Process for the production of polyisocyanate organic silicate solid/cellular solid product BLOUNT DAVID H 1979-05-08 US claimed
US-3981831-A REACTION OF ORGANIC POLYISOCYANATE WITH ALKALI METAL SILICATE OR SILICA SOL BAYER AKTIENGESELLSCHAFT (DT) 1976-09-21 US claimed
JP-8245535-A None JP disclosed
CN-120077027-A Sulfonylimide compounds as inhibitors of histone deacetylase 6 and pharmaceutical compositions comprising the same 株式会社钟根堂 2025-05-30 CN disclosed
CN-119630282-A Herbicidal compositions comprising alkyl polyglycosides 巴斯夫欧洲公司 2025-03-14 CN disclosed
US-3981831-A REACTION OF ORGANIC POLYISOCYANATE WITH ALKALI METAL SILICATE OR SILICA SOL BAYER AKTIENGESELLSCHAFT (DT) 1976-09-21 US disclosed
US-3971797-A ANTIARTHRITIC MERCK & CO., INC. (US) 1976-07-27 US disclosed
US-3937824-A COMPOSITIONS AND METHODS OF KILLING INSECTS AND ACARIDS USING ALKOXYIMINO CARBAMOYLOXY PHOSPHORUS COMPOUNDS VELSICOL CHEMICAL CORPORATION (US) 1976-02-10 US disclosed
US-3933756-A Process of preparation of synthetic resins by reacting a cross-linked isocyanate polyaddition product with low molecular weight polyisocyanate followed by reaction with an amino alkyl silane BAYER AKTIENGESELLSCHAFT (DT) 1976-01-20 US disclosed