Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 11/20 | 0.49 |
| ▸ | AVPR1B | P47901 | 8/20 | 0.49 |
| ▸ | AVPR2 | P30518 | 13/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MTTP | P55157 | 2/20 | 0.39 |
| ▸ | SPTLC2 | O15270 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972086 | 0.95 | AVPR1A (0.51) | AVPR1AAVPR1BAVPR2MTTP | |
| SCHEMBL6967089 | 0.88 | AVPR1A (0.46) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL6964965 | 0.84 | AVPR1A (0.50) | AVPR1AAVPR1BAVPR2MEN1USP2 | |
| SCHEMBL6971506 | 0.82 | AVPR1A (0.54) | AVPR1AAVPR1BAVPR2CYP2C9MTTP | |
| SCHEMBL6970749 | 0.81 | AVPR2 (0.55) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL6971739 | 0.80 | AVPR1A (0.50) | AVPR1AAVPR1BAVPR2SMN1; SMN2CYP2C9 | |
| SCHEMBL8961714 | 0.78 | AVPR1A (0.53) | AVPR1AAVPR1BAVPR2MEN1USP2 | |
| SCHEMBL6972082 | 0.78 | AVPR1A (0.52) | AVPR1AAVPR1BAVPR2MTTP | |
| SCHEMBL6957855 | 0.78 | AVPR1A (0.54) | AVPR1AAVPR1BAVPR2MTTP | |
| SCHEMBL6965230 | 0.76 | AVPR1A (0.56) | AVPR1AAVPR1BAVPR2MTTP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |