Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 9/20 | 0.46 |
| ▸ | AVPR1B | P47901 | 7/20 | 0.46 |
| ▸ | AVPR2 | P30518 | 10/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972086 | 0.93 | AVPR1A (0.51) | AVPR1AAVPR1BAVPR2LMNATP53 | |
| SCHEMBL6964969 | 0.88 | AVPR1A (0.49) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL6967087 | 0.83 | AVPR1A (0.47) | AVPR1AAVPR1BAVPR2LMNATP53 | |
| SCHEMBL9414294 | 0.81 | AVPR1A (0.47) | AVPR1AAVPR1BAVPR2LMNATP53 | |
| SCHEMBL8961732 | 0.79 | AVPR1A (0.47) | AVPR1AAVPR1BAVPR2LMNATP53 | |
| SCHEMBL6969281 | 0.79 | AVPR1A (0.51) | AVPR1AAVPR1BAVPR2LMNATP53 | |
| SCHEMBL6970232 | 0.77 | AVPR1A (0.47) | AVPR1AAVPR1BAVPR2LMNATP53 | |
| SCHEMBL6970749 | 0.76 | AVPR2 (0.55) | AVPR1AAVPR1BAVPR2 | |
| SCHEMBL6972082 | 0.76 | AVPR1A (0.52) | AVPR1AAVPR1BAVPR2LMNATP53 | |
| SCHEMBL8961670 | 0.75 | AVPR1A (0.45) | AVPR1AAVPR1BAVPR2LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |