Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 13/20 | 0.54 |
| ▸ | AVPR1B | P47901 | 10/20 | 0.54 |
| ▸ | AVPR2 | P30518 | 14/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MTTP | P55157 | 2/20 | 0.42 |
| ▸ | SPTLC2 | O15270 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965230 | 0.94 | AVPR1A (0.56) | AVPR1AAVPR1BAVPR2MTTPTP53 | |
| SCHEMBL6970821 | 0.93 | AVPR1A (0.57) | AVPR1AAVPR1BAVPR2MTTP | |
| SCHEMBL6971739 | 0.93 | AVPR1A (0.50) | AVPR1AAVPR1BAVPR2CYP2C9MTTP | |
| SCHEMBL6966347 | 0.92 | AVPR2 (0.44) | AVPR1AAVPR1BAVPR2CYP2C9MTTP | |
| SCHEMBL6964965 | 0.91 | AVPR1A (0.50) | AVPR1AAVPR1BAVPR2CYP2C9MTTP | |
| SCHEMBL6965369 | 0.88 | AVPR2 (0.54) | AVPR1AAVPR1BAVPR2CYP2C9 | |
| SCHEMBL6959303 | 0.87 | AVPR1A (0.52) | AVPR1AAVPR1BAVPR2MTTPTP53 | |
| SCHEMBL6967424 | 0.85 | AVPR2 (0.46) | AVPR1AAVPR1BAVPR2MTTPTP53 | |
| SCHEMBL6968185 | 0.85 | AVPR1A (0.54) | AVPR1AAVPR1BAVPR2MTTP | |
| SCHEMBL6972082 | 0.85 | AVPR1A (0.52) | AVPR1AAVPR1BAVPR2MTTPTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |