Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967216 | 0.88 | POLB (0.42) | POLBMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL1815924 | 0.80 | POLB (0.68) | POLBMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL7992188 | 0.77 | L3MBTL1 (0.34) | POLBMAPTALDH1A1KMT2ACYP1A2 | |
| SCHEMBL2477903 | 0.77 | KDM4E (0.56) | POLBALDH1A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL28235381 | 0.77 | GAA (0.50) | POLBMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL6971685 | 0.73 | GAA (0.39) | HPGDGAA | |
| SCHEMBL15576179 | 0.70 | HSD17B3 (0.41) | POLBMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL23360756 | 0.70 | MAPT (0.40) | POLBMAPTALDH1A1HPGDKMT2A | |
| SCHEMBL4768910 | 0.69 | POLB (0.63) | POLBMAPTALDH1A1HPGDKMT2A | |
| SCHEMBL10353001 | 0.69 | SMN1; SMN2 (0.31) | MAPTALDH1A1HSD17B10KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |