Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965037 | 0.88 | POLB (0.44) | POLBALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL10973768 | 0.78 | POLB (0.67) | POLBALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL6967633 | 0.77 | POLB (0.42) | POLBALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL6971685 | 0.76 | GAA (0.39) | HPGDGAA | |
| SCHEMBL13434933 | 0.75 | GAA (0.57) | POLBALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL162548 | 0.75 | CA9 (0.46) | ALDH1A1MAPTHPGDGAACA1 | |
| SCHEMBL18281195 | 0.75 | ALDH1A1 (0.53) | POLBALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL7985505 | 0.75 | — | — | |
| SCHEMBL23360756 | 0.73 | MAPT (0.40) | POLBALDH1A1MAPTHPGDGAA | |
| SCHEMBL7941329 | 0.72 | ALDH1A1 (0.53) | POLBALDH1A1MAPTHPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |