Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 11/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.53 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.51 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.51 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.48 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD5 | P21918 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967273 | 0.89 | PDK2 (0.45) | LTA4HHRH3PSMB1PSMB5PSMB2 | |
| SCHEMBL7510883 | 0.88 | HRH3 (0.44) | LTA4HHRH3PSMB1PSMB5PSMB2 | |
| SCHEMBL7442242 | 0.87 | LTA4H (0.69) | LTA4HHRH3PSMB1PSMB5PSMB2 | |
| SCHEMBL7511215 | 0.85 | LTA4H (0.43) | LTA4HHRH3PDK2DRD1DRD4 | |
| SCHEMBL6961166 | 0.84 | LTA4H (0.47) | LTA4HHRH3PSMB1PSMB5PSMB2 | |
| SCHEMBL6964901 | 0.83 | LTA4H (0.61) | LTA4HHRH3PSMB1PSMB5PSMB2 | |
| SCHEMBL7349591 | 0.83 | LTA4H (0.70) | LTA4HHRH3PSMB1PSMB5PSMB2 | |
| SCHEMBL7348199 | 0.83 | ESR1 (0.65) | LTA4HHRH3PSMB1PSMB5PSMB2 | |
| SCHEMBL7444253 | 0.83 | LTA4H (0.61) | LTA4HHRH3PSMB1PSMB5PSMB2 | |
| SCHEMBL7353997 | 0.83 | LTA4H (0.61) | LTA4HHRH3PSMB1PSMB5PSMB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980367-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2003-03-19 | — | — | EP | disclosed |
| EP-0980367-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998049161-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |