Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.43 |
| ▸ | LTA4H | P09960 | 3/20 | 0.42 |
| ▸ | BACE1 | P56817 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 3/20 | 0.41 |
| ▸ | DRD1 | P21728 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | DRD5 | P21918 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7511215 | 0.91 | LTA4H (0.43) | HRH3PDK2LTA4HBACE1POLB | |
| SCHEMBL6967273 | 0.89 | PDK2 (0.45) | HRH3PDK2LTA4HBACE1POLB | |
| SCHEMBL6965066 | 0.88 | LTA4H (0.54) | HRH3PDK2LTA4HMEN1KMT2A | |
| SCHEMBL7517414 | 0.86 | PDK2 (0.41) | PDK2LTA4HBACE1POLBMEN1 | |
| Oxalic Acid SCHEMBL6605838 | 0.81 | F2 (0.48) | HRH3KCNH2 | |
| Lithium Ion SCHEMBL6611336 | 0.77 | LTA4H (0.39) | HRH3PDK2LTA4HPOLBMEN1 | |
| SCHEMBL7442242 | 0.77 | LTA4H (0.69) | HRH3LTA4HHRH1DRD1DRD4 | |
| SCHEMBL7348199 | 0.75 | ESR1 (0.65) | HRH3LTA4HPSMB1PSMB5PSMB2 | |
| SCHEMBL6611328 | 0.74 | F2 (0.49) | — | |
| Lithium SCHEMBL6611346 | 0.74 | F2 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244655-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001036414-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2001-05-25 | — | — | WO | disclosed |