Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 9/20 | 0.42 |
| ▸ | MAOA | P21397 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987732 | 0.81 | MEN1 (0.49) | MAOBMAOAMEN1KMT2A | |
| SCHEMBL29602962 | 0.79 | FFAR1 (0.59) | CYP3A4 | |
| SCHEMBL377641 | 0.79 | FFAR1 (0.59) | CYP3A4 | |
| SCHEMBL6959497 | 0.78 | MAOB (0.55) | CYP3A4MAOBMAOAALOX5 | |
| SCHEMBL377642 | 0.77 | CYP3A4 (0.46) | CYP3A4IP6K1MAOBMAOANPC1 | |
| SCHEMBL8172462 | 0.77 | MAOB (0.48) | CYP3A4IP6K1MAOBMAOANPC1 | |
| SCHEMBL8315754 | 0.75 | FFAR1 (0.48) | MAOBMAOAMEN1KMT2A | |
| SCHEMBL6956120 | 0.74 | FFAR1 (0.63) | — | |
| SCHEMBL18571362 | 0.73 | CYP3A4 (0.61) | CYP3A4MAOBNPC1ALOX5PDGFRB | |
| SCHEMBL6958784 | 0.72 | FFAR1 (0.58) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787725-B1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-5693651-A | HYPOGLYCEMIC AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-12-02 | — | — | US | disclosed |
| EP-0787725-A1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-08-06 | — | — | EP | disclosed |