Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965592 | 0.80 | MMP8 (0.56) | KMT2AMEN1LMNATSHRSLC6A3 | |
| SCHEMBL3598733 | 0.78 | KMT2A (0.69) | KMT2AMEN1PTGS1PTGS2ALDH1A1 | |
| SCHEMBL1578804 | 0.78 | KMT2A (0.69) | KMT2APTGS1PTGS2ALDH1A1LMNA | |
| Mandelic Acid, Methyl Ester SCHEMBL28228867 | 0.77 | KMT2A (0.67) | KMT2AMEN1PTGS1PTGS2ALDH1A1 | |
| SCHEMBL5544986 | 0.77 | KMT2A (0.67) | KMT2AMEN1PTGS1PTGS2ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL27830689 | 0.77 | KMT2A (0.67) | KMT2AMEN1PTGS1PTGS2ALDH1A1 | |
| SCHEMBL6003332 | 0.77 | KMT2A (0.67) | KMT2AMEN1PTGS1PTGS2ALDH1A1 | |
| SCHEMBL5537242 | 0.77 | KMT2A (0.67) | KMT2AMEN1PTGS1PTGS2ALDH1A1 | |
| SCHEMBL183940 | 0.77 | KMT2A (0.67) | KMT2AMEN1PTGS1PTGS2ALDH1A1 | |
| Mandelic Acid, Methyl Ester SCHEMBL186900 | 0.77 | KMT2A (0.67) | KMT2AMEN1PTGS1PTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-6444616-B1 | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-03 | — | — | US | disclosed |
| US-6130225-A | Substituted p-trifluoromethylphenyluracils | BAYER AKTIENGESELLSCHAFT (DE) | 2000-10-10 | — | — | US | disclosed |