SCHEMBL3598733

SCHEMBL3598733

COC(=O)C(C(=O)OC)c1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.69
ALDH1A1 P00352 4/20 0.59
MMP8 P22894 1/20 0.58
SRC P12931 1/20 0.56
MEN1 O00255 2/20 0.50
LMNA P02545 2/20 0.50
PTGS1 P23219 1/20 0.50
PTGS2 P35354 1/20 0.50
GLS O94925 1/20 0.49
SLC6A3 Q01959 4/20 0.49
SLC6A2 P23975 2/20 0.49
SLC6A4 P31645 1/20 0.49
DHFR P00374 1/20 0.49
TSHR P16473 1/20 0.47
TDP1 Q9NUW8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL27830689 0.98 KMT2A (0.67) KMT2AALDH1A1MMP8SRCMEN1
SCHEMBL2914808 0.91 KMT2A (0.64) KMT2AALDH1A1MMP8SRCMEN1
SCHEMBL28474562 0.90 MMP8 (0.73) KMT2AALDH1A1MMP8MEN1GLS
SCHEMBL2227571 0.90 KMT2A (0.62) KMT2AALDH1A1MMP8SRCMEN1
SCHEMBL6959628 0.90 KMT2A (0.62) KMT2AALDH1A1MMP8SRCMEN1
SCHEMBL11031397 0.90 KMT2A (0.62) KMT2AALDH1A1MMP8SRCMEN1
SCHEMBL29002097 0.89 KMT2A (0.56) KMT2AALDH1A1MMP8SRCMEN1
SCHEMBL11679477 0.88 KMT2A (0.60) KMT2AALDH1A1MMP8SRCMEN1
SCHEMBL13158250 0.86 KMT2A (0.58) KMT2AALDH1A1MMP8SRCMEN1
SCHEMBL6818648 0.85 ALDH1A1 (0.54) KMT2AALDH1A1MMP8PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118222769-A Multi-carboxylic acid group high-absorption chrome tanning auxiliary agent containing barbituric acid structure and preparation method thereof 南京工业大学 2024-06-21 CN claimed
CN-109896684-B Sewage pretreatment process in organic product preparation process 李德祥 2021-12-24 CN claimed
CN-110467575-A The synthesis preparation method of forensic science qualitative, quantitative phenobarbital-D5 INST FORENSIC SCIENCE MINI PUBLIC SECURITY PRC 2019-11-19 CN claimed
CN-109896684-A A kind of pre-treating process for sewage in organic products preparation process 李德祥 2019-06-18 CN claimed
CN-102344516-A (Alkyl)fluoroalkyl acrylate polymer containing terminal alkyl ester or terminal carboxylic acid, its preparation and application CAS GUANGZHOU CHEMISTRY CO LTD 2012-02-08 CN claimed
CN-100455668-C Enzyme-catalyzed polyamides and compositions and processes of preparing and using same HERCULES INC (US) 2009-01-28 CN claimed
US-7252784-B2 Cyclic ketone peroxide formulations AKZO NOBEL N.V. (NL) 2007-08-07 US claimed
US-6677427-B1 REACTING AT LEAST ONE DIESTER AND AT LEAST ONE POLYAMINE IN PRESENCE OF A HYDROLYTIC ENZYME TO PREPARE POLYAMIDE HERCULES INCORPORATED 2004-01-13 US claimed
CN-1436244-A Enzyme-catalyzed polyamides and compositions thereof, and methods for their preparation and use HERCULES INC (US) 2003-08-13 CN claimed
EP-1290211-A2 ENZYME-CATALYZED POLYAMIDES AND COMPOSITIONS AND PROCESSES OF PREPARING AND USING THE SAME HERCULES INCORPORATED (US) 2003-03-12 EP claimed
WO-2001096588-A2 ENZYME-CATALYZED POLYAMIDES AND COMPOSITIONS AND PROCESSES OF PREPARING AND USING THE SAME HERCULES INCORPORATED (US) 2001-12-20 WO claimed
US-12565493-B2 Method for preparing 2-[2-(2-chlorothiazol-5-yl)-2-oxo-ethyl]sulfanyl-6-hydroxy-3-methyl-5-phenyl-pyrimidin-4-one BASF SE (DE) 2026-03-03 US disclosed
EP-4569008-A1 CARBONATE COMPOUNDS AS ACTIVITY LIMITING AGENTS IN ZIEGLER-NATTA CATALYST COMPOSITIONS FOR OLEFIN POLYMERIZATION Formosa Plastics Corporation, U.S.A. (US) 2025-06-18 EP disclosed
CN-118222769-A Multi-carboxylic acid group high-absorption chrome tanning auxiliary agent containing barbituric acid structure and preparation method thereof 南京工业大学 2024-06-21 CN disclosed
CN-118186152-A Multifunctional high-absorption chrome tanning auxiliary agent containing barbituric acid structure and preparation method thereof 南京工业大学 2024-06-14 CN disclosed
US-5112864-A Inhibitors of phospholipase enzymes by treatment with oxo alkynyl furan, thiophene or benzene carboxylic acid derivative G. D. SEARLE & CO. (US) 1992-05-12 US disclosed
US-5102667-A Antiallergens, antiinflammatory agents, nervous system disorders, immunology, psychological disorders RHONE-POULENC SANTE (FR) 1992-04-07 US disclosed
EP-0433024-A1 Colour recording medium containing leuco dye FUJI PHOTO FILM CO., LTD. (JP) 1991-06-19 EP disclosed
US-4562185-A INSECTICIDES; MITICIDES BAYER AKTIENGESELLSCHAFT (DE) 1985-12-31 US disclosed
US-4076601-A FROM DIMETHYL MALONATE MONSANTO COMPANY (US) 1978-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12565493-B2 Method for preparing 2-[2-(2-chlorothiazol-5-yl)-2-oxo-ethyl]sulfanyl-6-hydroxy-3-methyl-5-phenyl-pyrimidin-4-one TPMT, UMPS, TST KMT2A 1341/4885ALDH1A1 213/4885MMP8 4182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.