Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 9/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.49 |
| ▸ | RHEB | Q15382 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 8/20 | 0.44 |
| ▸ | HTR2B | P41595 | 8/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23709615 | 0.92 | RHEB (0.48) | HTR1ASLC6A2RHEBSLC6A4SLC6A3 | |
| SCHEMBL6493863 | 0.76 | HTR6 (0.58) | — | |
| Hydrochloric Acid SCHEMBL6504505 | 0.75 | HTR6 (0.57) | — | |
| SCHEMBL6956528 | 0.74 | SLC6A2 (0.56) | HTR1ASLC6A2HTR2CHTR2BSLC6A4 | |
| Hydrochloric Acid SCHEMBL6528932 | 0.74 | HTR6 (0.47) | HTR1ASLC6A2HTR2CHTR2BPIM1 | |
| SCHEMBL6495270 | 0.74 | HTR6 (0.60) | HTR1A | |
| SCHEMBL6502257 | 0.73 | HTR6 (0.50) | HTR1ASLC6A2PIM1PIM2 | |
| SCHEMBL6500751 | 0.73 | HTR6 (0.51) | PIM1PIM2 | |
| Hydrochloric Acid SCHEMBL6962825 | 0.73 | SLC6A2 (0.55) | HTR1ASLC6A2HTR2CHTR2BSLC6A4 | |
| Hydrochloric Acid SCHEMBL6169239 | 0.72 | HTR1A (0.48) | HTR1ASLC6A2HTR2CSLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863136-B1 | Derivatives of azetidine and pyrrolidine | AKZO NOBEL NV (NL) | 2003-09-24 | — | — | EP | claimed |