Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.73 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | F13A1 | P00488 | 1/20 | 0.64 |
| ▸ | ACACB | O00763 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.55 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19668112 | 0.87 | SMN1; SMN2 (0.69) | SMN1; SMN2NPC1RAB9AKDM4EF13A1 | |
| SCHEMBL9975933 | 0.85 | SMN1; SMN2 (0.67) | SMN1; SMN2NPC1RAB9AKDM4EF13A1 | |
| SCHEMBL20380008 | 0.85 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1RAB9AKDM4EF13A1 | |
| SCHEMBL10592850 | 0.85 | KDM4E (0.84) | SMN1; SMN2KDM4EF13A1ACACBALDH1A1 | |
| SCHEMBL659053 | 0.84 | SMN1; SMN2 (1.00) | SMN1; SMN2NPC1RAB9AKDM4EF13A1 | |
| SCHEMBL28777913 | 0.84 | SMN1; SMN2 (0.57) | SMN1; SMN2NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL9081470 | 0.83 | LMNA (0.61) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL1629783 | 0.83 | SMN1; SMN2 (0.57) | SMN1; SMN2NPC1RAB9AKDM4EF13A1 | |
| SCHEMBL10568565 | 0.82 | KMT2A (0.58) | SMN1; SMN2NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL15926905 | 0.82 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1RAB9AKDM4EF13A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6352993-B1 | ANTIULCER AGENTS | YUHAN CORPORATION (KR) | 2002-03-05 | — | — | US | disclosed |
| EP-1015444-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION, LTD. (KR) | 2000-07-05 | — | — | EP | disclosed |
| WO-1998043968-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 1998-10-08 | — | — | WO | disclosed |