Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | ACACB | O00763 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | F13A1 | P00488 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965266 | 0.85 | SMN1; SMN2 (0.73) | SMN1; SMN2ACACBKDM4EF13A1ALDH1A1 | |
| SCHEMBL12039535 | 0.84 | KMT2A (0.53) | SMN1; SMN2ALDH1A1HIF1AKMT2AESR1 | |
| SCHEMBL26698316 | 0.84 | KMT2A (0.53) | SMN1; SMN2ALDH1A1HIF1AKMT2AESR1 | |
| SCHEMBL15926905 | 0.84 | SMN1; SMN2 (0.61) | SMN1; SMN2ACACBKDM4EF13A1ALDH1A1 | |
| SCHEMBL19668112 | 0.83 | SMN1; SMN2 (0.69) | SMN1; SMN2ACACBKDM4EF13A1ALDH1A1 | |
| SCHEMBL8528146 | 0.81 | CA2 (0.50) | SMN1; SMN2ACACBKDM4EALDH1A1HIF1A | |
| SCHEMBL10592850 | 0.81 | KDM4E (0.84) | SMN1; SMN2ACACBKDM4EF13A1ALDH1A1 | |
| SCHEMBL12475741 | 0.81 | ACACB (0.86) | SMN1; SMN2ACACBKDM4EF13A1ALDH1A1 | |
| SCHEMBL659053 | 0.80 | SMN1; SMN2 (1.00) | SMN1; SMN2ACACBKDM4EF13A1ALDH1A1 | |
| SCHEMBL20593516 | 0.80 | THRB (0.64) | SMN1; SMN2ALDH1A1HIF1AKMT2AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796003-B1 | Label free kinase assays and reagents | PLEXERA, LLC (US) | 2014-08-05 | — | — | US | disclosed |
| US-8263377-B2 | Label free kinase assays and reagents | PLEXERA, LLC (US) | 2012-09-11 | — | — | US | disclosed |
| US-20120157328-A1 | Label Free Kinase Assays and Reagents | SUZHOU PUXIN LIFE SCIENCE & TECHNOLOGY., LTD. (CN) | 2012-06-21 | — | — | US | disclosed |