Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 15/20 | 0.51 |
| ▸ | CTSB | P07858 | 7/20 | 0.46 |
| ▸ | CTSK | P43235 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966523 | 0.92 | CTSS (0.51) | CTSSCTSBCTSKCTSL | |
| SCHEMBL6957068 | 0.90 | CTSS (0.52) | CTSSCTSBCTSKCTSL | |
| SCHEMBL6106816 | 0.89 | CTSS (0.65) | CTSSCTSBCTSKCTSL | |
| SCHEMBL6968079 | 0.87 | CTSS (0.48) | CTSSCTSBCTSKCTSL | |
| SCHEMBL6976139 | 0.85 | CTSS (0.64) | CTSSCTSBCTSL | |
| SCHEMBL6972400 | 0.85 | CTSS (0.55) | CTSSCTSBCTSKCTSL | |
| SCHEMBL6967060 | 0.82 | CTSS (0.45) | CTSSCTSBCTSKCTSL | |
| SCHEMBL6348945 | 0.82 | CTSS (0.49) | CTSSCTSBCTSKSMN1; SMN2CTSL | |
| SCHEMBL6348947 | 0.82 | CTSS (0.49) | CTSSCTSBCTSKSMN1; SMN2CTSL | |
| SCHEMBL6968559 | 0.82 | CTSS (0.69) | CTSSCTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218372-B1 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMA (US) | 2003-07-02 | — | — | EP | claimed |