Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 19/20 | 0.48 |
| ▸ | CTSL | P07711 | 3/20 | 0.44 |
| ▸ | CTSB | P07858 | 14/20 | 0.42 |
| ▸ | CTSK | P43235 | 14/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967060 | 0.95 | CTSS (0.45) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6972400 | 0.91 | CTSS (0.55) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6972419 | 0.89 | CTSL (0.53) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6974668 | 0.87 | CTSL (0.45) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6965345 | 0.87 | CTSS (0.51) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6961400 | 0.86 | CTSS (0.50) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6107557 | 0.86 | CTSS (0.64) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6967564 | 0.85 | CTSS (0.43) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6966523 | 0.85 | CTSS (0.51) | CTSSCTSLCTSBCTSK | |
| SCHEMBL7070928 | 0.84 | CTSS (0.53) | CTSSCTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218372-B1 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMA (US) | 2003-07-02 | — | — | EP | claimed |