Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 16/20 | 0.54 |
| ▸ | AVPR1A | P37288 | 9/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | OXTR | P30559 | 1/20 | 0.49 |
| ▸ | AVPR1B | P47901 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964270 | 0.94 | AVPR2 (0.53) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL6963025 | 0.91 | AVPR2 (0.57) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL6969947 | 0.91 | AVPR2 (0.58) | AVPR2AVPR1ACYP2C9OXTRAVPR1B | |
| SCHEMBL6958676 | 0.91 | AVPR2 (0.53) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL6969840 | 0.91 | AVPR2 (0.53) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL6966347 | 0.90 | AVPR2 (0.44) | AVPR2AVPR1ACYP2C9OXTRAVPR1B | |
| SCHEMBL6972761 | 0.90 | AVPR2 (0.52) | AVPR2AVPR1ACYP2C9OXTRAVPR1B | |
| SCHEMBL6969714 | 0.89 | AVPR2 (0.49) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL8961713 | 0.89 | AVPR2 (0.49) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL6971506 | 0.88 | AVPR1A (0.54) | AVPR2AVPR1ACYP2C9AVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |