Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 11/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 7/20 | 0.44 |
| ▸ | OXTR | P30559 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MTTP | P55157 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967424 | 0.94 | AVPR2 (0.46) | AVPR2AVPR1AOXTRAVPR1BALDH1A1 | |
| SCHEMBL6972475 | 0.92 | AVPR2 (0.48) | AVPR2AVPR1AOXTRAVPR1BALDH1A1 | |
| SCHEMBL6967409 | 0.92 | AVPR2 (0.48) | AVPR2AVPR1AOXTRCYP2C9AVPR1B | |
| SCHEMBL6971506 | 0.92 | AVPR1A (0.54) | AVPR2AVPR1ACYP2C9AVPR1BMTTP | |
| SCHEMBL6965369 | 0.90 | AVPR2 (0.54) | AVPR2AVPR1AOXTRCYP2C9AVPR1B | |
| SCHEMBL6970903 | 0.90 | AVPR2 (0.46) | AVPR2AVPR1AOXTRCYP2C9AVPR1B | |
| SCHEMBL6960416 | 0.86 | AVPR1A (0.55) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL6971642 | 0.85 | AVPR2 (0.50) | AVPR2AVPR1AOXTRAVPR1BALDH1A1 | |
| SCHEMBL6965230 | 0.85 | AVPR1A (0.56) | AVPR2AVPR1AAVPR1BMTTP | |
| SCHEMBL8961667 | 0.84 | AVPR2 (0.47) | AVPR2AVPR1AOXTRAVPR1BMTTP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |