Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.70 |
| ▸ | CYP11B1 | P15538 | 9/20 | 0.65 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | QPCT | Q16769 | 1/20 | 0.62 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.62 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.62 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.56 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.56 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30523909 | 0.87 | CYP11B1 (0.76) | CYP19A1CYP11B1CYP11B2POLBTBXAS1 | |
| SCHEMBL15179016 | 0.87 | CYP11B1 (0.76) | CYP19A1CYP11B1CYP11B2POLBTBXAS1 | |
| SCHEMBL30523908 | 0.87 | CYP11B1 (0.76) | CYP19A1CYP11B1CYP11B2POLBTBXAS1 | |
| SCHEMBL3980782 | 0.86 | POLB (0.58) | CYP19A1CYP11B1CYP11B2POLBTBXAS1 | |
| SCHEMBL11950647 | 0.83 | CYP11B1 (0.62) | CYP19A1CYP11B1CYP11B2POLBTBXAS1 | |
| SCHEMBL11624611 | 0.83 | CYP11B1 (0.58) | CYP19A1CYP11B1CYP11B2POLBTBXAS1 | |
| SCHEMBL11607374 | 0.83 | ALDH1A1 (0.57) | CYP19A1CYP11B1CYP11B2POLBTBXAS1 | |
| SCHEMBL11624547 | 0.82 | CYP11B1 (0.57) | CYP19A1CYP11B1CYP11B2POLBTBXAS1 | |
| SCHEMBL28140257 | 0.80 | CYP11B1 (0.59) | CYP19A1CYP11B1CYP11B2POLBTBXAS1 | |
| SCHEMBL241 | 0.80 | CYP11B1 (0.67) | CYP19A1CYP11B1CYP11B2POLBTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023274257-A1 | IMIDAZOLE COMPOUND, AND INTERMEDIATE AND APPLICATION THEREOF | 诸葛国琴 | 2023-01-05 | — | — | WO | disclosed |
| CN-101420970-A | Implantable sensors and implantable pumps and anti-scarring agents | ANGIOTECH INT AG (CH) | 2009-04-29 | — | — | CN | disclosed |
| CN-101420991-A | Polymer compositions and methods for their use | ANGIOTECH INT AG (CH) | 2009-04-29 | — | — | CN | disclosed |
| CN-101094613-A | Medical implant and anti-scarring agent | ANGIOTECH INT AG (CH) | 2007-12-26 | — | — | CN | disclosed |
| CN-1878514-A | Soft tissue implants and anti-scarring agents | ANGIOTECH INT AG (CH) | 2006-12-13 | — | — | CN | disclosed |
| CN-1878594-A | Electrical devices and anti-scarring agents | ANGIOTECH INT AG (CH) | 2006-12-13 | — | — | CN | disclosed |
| EP-0955294-B1 | Imidazolyl-alkenoic acid | SMITHKLINE BEECHAM CORP (US) | 2003-09-24 | — | — | EP | disclosed |
| EP-0563238-B1 | IMIDAZOLYL-ALKENOIC ACIDS | SMITHKLINE BEECHAM CORP (US) | 2002-05-22 | — | — | EP | disclosed |
| EP-0403159-B1 | Imidazolyl-alkenoic acids | SMITHKLINE BEECHAM CORP (US) | 2000-03-01 | — | — | EP | disclosed |
| EP-0955294-A2 | Imidazolyl-alkenoic acid | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-10 | — | — | EP | disclosed |
| EP-0425211-A1 | Substituted 5-((tetrazolyl)alkenyl)-imidazoles | SMITHKLINE BEECHAM CORPORATION (US) | 1991-05-02 | — | — | EP | disclosed |
| EP-0403158-A2 | Imidazolyl-alkenoic acids | SMITHKLINE BEECHAM CORPORATION (US) | 1990-12-19 | — | — | EP | disclosed |
| EP-0403159-A2 | Imidazolyl-alkenoic acids | SMITHKLINE BEECHAM CORPORATION (US) | 1990-12-19 | — | — | EP | disclosed |
| EP-0276583-A1 | Imidazole derivatives, processes for their preparation and their fungicidal properties | Instituto de Investigacion Y Desarrollo Quimico Biologico S.A. (ES) | 1988-08-03 | — | — | EP | disclosed |
| EP-0003560-B1 | IMIDAZOLE DERIVATIVES AND SALTS THEREOF, THEIR SYNTHESIS, AND PHARMACEUTICAL FORMULATIONS | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-05-02 | — | — | EP | disclosed |
| EP-0106060-A2 | Imidazole derivatives and salts thereof, their synthesis, and pharmaceutical formulations | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-04-25 | — | — | EP | disclosed |
| US-4431815-A | CARDIOTONIC AND ANTISHOCK AGENTS; ANTICOAGULANTS | BURROUGHS WELLCOME CO. (US) | 1984-02-14 | — | — | US | disclosed |
| EP-0003560-A2 | Imidazole derivatives and salts thereof, their synthesis, and pharmaceutical formulations | THE WELLCOME FOUNDATION LIMITED (GB) | 1979-08-22 | — | — | EP | disclosed |
| US-4073922-A | BIS-PHENYL(2-HALOPHENYL)-1-IMIDAZOLYL METHANE | Simoons, John R. A. (US) | 1978-02-14 | — | — | US | disclosed |
| US-4073922-A | BIS-PHENYL(2-HALOPHENYL)-1-IMIDAZOLYL METHANE | Simoons, John R. A. (US) | 1978-02-14 | — | — | US | disclosed |