Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL707038 | 0.87 | CTSS (0.46) | CTSS | |
| SCHEMBL696265 | 0.87 | CTSS (0.46) | CTSS | |
| SCHEMBL695503 | 0.86 | CTSS (0.45) | CTSSAR | |
| SCHEMBL695949 | 0.86 | CTSS (0.41) | CTSS | |
| SCHEMBL696102 | 0.86 | CTSS (0.40) | CTSSAR | |
| SCHEMBL697004 | 0.85 | CTSS (0.39) | CTSSAR | |
| SCHEMBL695640 | 0.85 | CTSS (0.40) | CTSSAR | |
| SCHEMBL696992 | 0.85 | GPR119 (0.40) | CTSSAR | |
| SCHEMBL696142 | 0.85 | CTSS (0.38) | CTSSAR | |
| SCHEMBL695075 | 0.84 | CTSS (0.46) | CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421826-A1 | PROLINE DERIVATIVES AS CATHEPSIN INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2012-02-29 | — | — | EP | disclosed |
| WO-2010121918-A1 | PROLINE DERIVATIVES AS CATHEPSIN INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-10-28 | — | — | WO | disclosed |