Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.72 |
| ▸ | MEN1 | O00255 | 4/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | PKM | P14618 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | FNTA | P49354 | 1/20 | 0.59 |
| ▸ | FNTB | P49356 | 1/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.53 |
| ▸ | AHR | P35869 | 1/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4781191 | 0.85 | MAPT (0.74) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL27923847 | 0.84 | MAPT (0.72) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL29466101 | 0.84 | PKM (0.73) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL584367 | 0.84 | PKM (0.73) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL27477114 | 0.81 | MAPT (0.68) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL361312 | 0.81 | PKM (1.00) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL2003499 | 0.81 | MAPT (0.68) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL30419025 | 0.81 | PKM (1.00) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL2269868 | 0.81 | MAPT (0.68) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL29407882 | 0.81 | MAPT (0.72) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | claimed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |