Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | FAAH | O00519 | 2/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | FNTA | P49354 | 1/20 | 0.60 |
| ▸ | FNTB | P49356 | 1/20 | 0.60 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.57 |
| ▸ | APAF1 | O14727 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9660764 | 0.90 | HRH3 (0.64) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9418839 | 0.89 | HRH3 (0.67) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11136651 | 0.86 | MAPT (0.59) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9659449 | 0.83 | MEN1 (0.69) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4781191 | 0.83 | MAPT (0.74) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL27996401 | 0.83 | HRH3 (0.58) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11136033 | 0.82 | PKM (0.69) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21819729 | 0.82 | HRH3 (0.58) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13280575 | 0.82 | MAPT (0.60) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6965640 | 0.81 | MAPT (0.72) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964622-B2 | Indole acetic acid derivatives and their use as pharmaceutical agents | BAYER HEALTHCARE LLC (US) | 2011-06-21 | — | — | US | disclosed |
| US-20090298854-A1 | Indole acetic acid derivatives and their use as pharmaceutical agents | MA XIN | 2009-12-03 | — | — | US | disclosed |
| EP-1620088-A4 | INDOLE ACETIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICAL AGENTS | BAYER PHARMACEUTICALS CORP (US) | 2007-08-29 | — | — | EP | disclosed |
| EP-1620088-A2 | INDOLE ACETIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICAL AGENTS | Bayer Pharmaceuticals Corporation (US) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004098498-A2 | INDOLE ACETIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICAL AGENTS | BAYER PHARMACEUTICALS CORPORATION (US) | 2004-11-18 | — | — | WO | disclosed |
| WO-1994000986-A1 | PLANT GROWTH REGULATING COMPOSITIONS | CHURCH & DWIGHT COMPANY, INC. (US) | 1994-01-20 | — | — | WO | disclosed |
| US-4415350-A | ROOTING; TREES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF AGRICULTURE (US) | 1983-11-15 | — | — | US | disclosed |
| US-4411684-A | Auxin compositions of N-phenyl and N-chloro phenyl indolyl-3-alkylene amides and their use as auxin growth regulators | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1983-10-25 | — | — | US | disclosed |
| US-4297125-A | Tree rooting using synthetic auxins | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1981-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298854-A1 | Indole acetic acid derivatives and their use as pharmaceutical agents | IDO1, IDO2, AADAT | MAPT 1349/4885MEN1 2247/4885KMT2A 1083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.