Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 8/20 | 0.45 |
| ▸ | HTR1A | P08908 | 7/20 | 0.45 |
| ▸ | DRD1 | P21728 | 7/20 | 0.45 |
| ▸ | DRD4 | P21917 | 7/20 | 0.45 |
| ▸ | DRD5 | P21918 | 7/20 | 0.45 |
| ▸ | DRD2 | P14416 | 7/20 | 0.45 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971729 | 0.88 | CCR8 (0.52) | HTR1ACCR8 | |
| SCHEMBL6968017 | 0.87 | CCR8 (0.44) | DRD3HTR1ADRD1DRD4DRD5 | |
| SCHEMBL6966012 | 0.86 | CCR8 (0.42) | DRD3HTR1ADRD1DRD4DRD5 | |
| SCHEMBL6969343 | 0.85 | CCR8 (0.42) | DRD3HTR1ADRD1DRD4DRD5 | |
| SCHEMBL6970280 | 0.85 | CCR8 (0.44) | DRD3HTR1ADRD1DRD4DRD5 | |
| SCHEMBL6960454 | 0.84 | HTR1A (0.44) | DRD3HTR1ADRD1DRD4DRD5 | |
| SCHEMBL6960457 | 0.84 | HTR1A (0.44) | DRD3HTR1ADRD1DRD4DRD5 | |
| SCHEMBL6972423 | 0.84 | CCR8 (0.43) | HTR1ADRD2CCR8MAPT | |
| SCHEMBL6974682 | 0.84 | CCR8 (0.43) | HTR1ADRD2CCR8MAPT | |
| SCHEMBL6965276 | 0.83 | CCR8 (0.53) | CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051413-B1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2003-06-04 | — | — | EP | claimed |
| EP-1051413-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2000-11-15 | — | — | EP | claimed |
| WO-1999037635-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 1999-07-29 | — | — | WO | claimed |
| EP-1051413-B1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2003-06-04 | — | — | EP | disclosed |
| EP-1051413-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999037635-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 1999-07-29 | — | — | WO | disclosed |