Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12216187 | 0.86 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL6964767 | 0.76 | MGAM (0.35) | MGAMGAASIMGAM2SOAT1 | |
| SCHEMBL12192288 | 0.75 | — | — | |
| SCHEMBL11413136 | 0.74 | ALDH1A1 (0.41) | MGAMGAASIMGAM2SOAT1 | |
| SCHEMBL6955652 | 0.72 | — | — | |
| SCHEMBL10906052 | 0.71 | — | — | |
| SCHEMBL12216288 | 0.70 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL20387812 | 0.68 | SOAT1 (0.32) | SOAT1 | |
| SCHEMBL7865142 | 0.67 | — | — | |
| SCHEMBL13054038 | 0.67 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340751-B1 | REACTION OF IMIDAZOLONE WITH AMIDE AND MAGNESIUM COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-01-22 | — | — | US | claimed |
| EP-0974582-B1 | Process for the preparation of 4-substituted azetidinone derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 2003-02-12 | — | — | EP | disclosed |
| US-6340751-B1 | REACTION OF IMIDAZOLONE WITH AMIDE AND MAGNESIUM COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-0573667-B1 | PROCESS FOR PRODUCING 4-SUBSTITUTED AZETIDINONE DERIVATIVE | NIPPON SODA CO (JP) | 2001-06-13 | — | — | EP | disclosed |
| EP-0974582-A1 | Process for the preparation of 4-substituted azetidinone derivatives | Takasago International Corporation (JP) | 2000-01-26 | — | — | EP | disclosed |
| US-5731431-A | Process for preparing 4-substituted azetidinone derivatives | NIPPON SODA CO., LTD. (JP) | 1998-03-24 | — | — | US | disclosed |
| EP-0573667-A1 | PROCESS FOR PRODUCING 4-SUBSTITUTED AZETIDINONE DERIVATIVE | NIPPON SODA CO., LTD. (JP) | 1993-12-15 | — | — | EP | disclosed |