Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ADH1C | P00326 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970478 | 0.98 | ADH1A (0.37) | ADH1ACYP1A2ADH1CDRD3DRD2 | |
| SCHEMBL739057 | 0.92 | ADH1A (0.43) | ADH1ACYP1A2ADH1CDRD3DRD2 | |
| SCHEMBL736325 | 0.90 | DRD3 (0.42) | ADH1AADH1CDRD3DRD2DRD4 | |
| SCHEMBL6963963 | 0.90 | ADH1A (0.37) | ADH1ACYP1A2ADH1CDRD3DRD2 | |
| SCHEMBL6961343 | 0.90 | ADH1C (0.37) | ADH1AADH1CDRD3DRD2DRD4 | |
| SCHEMBL627799 | 0.90 | ADH1A (0.45) | ADH1ACYP1A2ADH1CDRD3DRD2 | |
| SCHEMBL2099636 | 0.88 | DRD3 (0.43) | ADH1AADH1CDRD3DRD2DRD4 | |
| Fluoride SCHEMBL9620624 | 0.88 | ADH1A (0.44) | ADH1ACYP1A2ADH1CDRD3DRD2 | |
| Bromide SCHEMBL28388955 | 0.88 | ADH1A (0.44) | ADH1ACYP1A2ADH1CDRD3DRD2 | |
| SCHEMBL517191 | 0.88 | ADH1A (0.43) | ADH1ACYP1A2ADH1CDRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0870765-B1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARM CO LTD (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-5981557-A | HAVING IMPROVING EFFECTS ON THE DYSMOTILITY IN THE GASTROINTESTINAL TRACT | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0870765-A1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-14 | — | — | EP | disclosed |