Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3861705 | 0.82 | HSD17B10 (0.55) | CYP1A2TSHRALDH1A1KMT2AHSD17B10 | |
| SCHEMBL9797804 | 0.82 | CYP1A2 (0.73) | CYP1A2TSHRALDH1A1KMT2AGPR35 | |
| SCHEMBL7126585 | 0.82 | HSD17B10 (0.55) | CYP1A2TSHRALDH1A1KMT2AHSD17B10 | |
| SCHEMBL14247407 | 0.81 | ALDH1A1 (0.50) | CYP1A2TSHRALDH1A1KMT2AHSD17B10 | |
| SCHEMBL29100171 | 0.81 | ALDH1A1 (0.53) | CYP1A2TSHRALDH1A1KMT2AHPGD | |
| SCHEMBL9450290 | 0.81 | CYP1A2 (0.46) | CYP1A2TSHRALDH1A1KMT2AHSD17B10 | |
| SCHEMBL6681084 | 0.80 | POLB (0.52) | CYP1A2TSHRALDH1A1KMT2AHSD17B10 | |
| SCHEMBL31279956 | 0.79 | ALDH1A1 (0.49) | CYP1A2TSHRALDH1A1KMT2AHSD17B10 | |
| SCHEMBL20946373 | 0.79 | ALDH1A1 (0.49) | CYP1A2TSHRALDH1A1KMT2AHSD17B10 | |
| SCHEMBL29100172 | 0.77 | GAA (0.55) | CYP1A2ALDH1A1KMT2ASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |