Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.46 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.46 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11597118 | 0.87 | CYP1A2 (0.73) | CYP1A2ALDH1A1GPR35TSHRTP53 | |
| SCHEMBL3291900 | 0.85 | CYP1A2 (1.00) | CYP1A2ALDH1A1GPR35TSHRTP53 | |
| SCHEMBL865986 | 0.85 | CYP1A2 (1.00) | CYP1A2ALDH1A1GPR35TSHRTP53 | |
| SCHEMBL11329796 | 0.83 | NPC1 (0.52) | CYP1A2ALDH1A1TSHRHPGDMAPK1 | |
| SCHEMBL3861705 | 0.83 | HSD17B10 (0.55) | CYP1A2ALDH1A1TSHRMAPK1TDP1 | |
| SCHEMBL31016518 | 0.83 | CYP1A2 (0.79) | CYP1A2ALDH1A1GPR35TSHRTP53 | |
| SCHEMBL29100171 | 0.82 | ALDH1A1 (0.53) | CYP1A2ALDH1A1TSHRHPGDMAPK1 | |
| SCHEMBL6965987 | 0.82 | CYP1A2 (0.50) | CYP1A2ALDH1A1GPR35TSHRTP53 | |
| SCHEMBL3032854 | 0.81 | CYP1A2 (0.71) | CYP1A2ALDH1A1GPR35TSHRTP53 | |
| SCHEMBL19329648 | 0.81 | CYP1A2 (0.69) | CYP1A2ALDH1A1GPR35TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160116448-A1 | pH-MODULATED QUENCHERS OF FLUORESCENCE | BERRY AND ASSOCIATES, INC. | 2016-04-28 | — | — | US | disclosed |
| EP-0163854-B1 | PROCESS FOR THE ELIMINATION OF FLUORESCENCE AND CATIONIC OR AMPHOTERIC AROMATIC NITRO COMPOUNDS | BAYER AG (DE) | 1991-02-27 | — | — | EP | disclosed |
| US-4695405-A | Process for quenching fluorescence, and new cationic or amphoteric aromatic nitro compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1987-09-22 | — | — | US | disclosed |
| EP-0163854-A2 | Process for the elimination of fluorescence and cationic or amphoteric aromatic nitro compounds | BAYER AG (DE) | 1985-12-11 | — | — | EP | disclosed |
| US-4038253-A | PHOTOCROSS-LINKABLE POLYMERS CONTAINING PENDANT DIAZOESTER GROUPS | HERCULES INCORPORATED (US) | 1977-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160116448-A1 | pH-MODULATED QUENCHERS OF FLUORESCENCE | NHERF1, ANXA5, ARFGEF1 | CYP1A2 1767/4885ALDH1A1 323/4885GPR35 4057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.