Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.76 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6961722 | 0.93 | ACHE (0.72) | ACHENPC1CYP3A4GAAPOLB | |
| SCHEMBL6971333 | 0.90 | ACHE (0.61) | ACHENPC1CYP3A4GAAPOLB | |
| Hydrochloric Acid SCHEMBL6971698 | 0.90 | ACHE (0.70) | ACHENPC1CYP3A4GAAPOLB | |
| Hydrochloric Acid SCHEMBL6973563 | 0.88 | ACHE (0.68) | ACHENPC1CYP3A4GAAPOLB | |
| SCHEMBL28440118 | 0.88 | ACHE (0.85) | ACHENPC1POLBLMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL6973844 | 0.86 | ACHE (0.81) | ACHENPC1POLBLMNAALDH1A1 | |
| Acotiamide SCHEMBL28293346 | 0.86 | ACHE (1.00) | ACHENPC1GAAPOLBLMNA | |
| Acotiamide SCHEMBL1043131 | 0.86 | ACHE (1.00) | ACHENPC1GAAPOLBLMNA | |
| Acotiamide SCHEMBL30872102 | 0.86 | ACHE (1.00) | ACHENPC1GAAPOLBLMNA | |
| SCHEMBL6976759 | 0.86 | ACHE (0.68) | ACHENPC1LMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0870765-B1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARM CO LTD (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-5981557-A | HAVING IMPROVING EFFECTS ON THE DYSMOTILITY IN THE GASTROINTESTINAL TRACT | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0870765-A1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-14 | — | — | EP | disclosed |