Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 8/20 | 0.44 |
| ▸ | NPC1 | O15118 | 7/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL434805 | 0.85 | MEN1 (0.61) | ALDH1A1MEN1KMT2APOLBESR1 | |
| SCHEMBL6972500 | 0.79 | MAPT (0.50) | ALDH1A1MEN1KMT2APOLBESR1 | |
| SCHEMBL1087642 | 0.77 | MAPT (0.56) | ALDH1A1MEN1KMT2AHPGDHSD17B10 | |
| SCHEMBL2190095 | 0.76 | MEN1 (0.52) | ALDH1A1MEN1KMT2APOLBESR1 | |
| SCHEMBL20181860 | 0.76 | CYP1A2 (0.58) | ALDH1A1MEN1KMT2APOLBESR1 | |
| SCHEMBL6961965 | 0.75 | NPC1 (0.41) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL28950613 | 0.73 | NPC1 (0.49) | ALDH1A1MEN1KMT2APOLBESR1 | |
| SCHEMBL27759338 | 0.73 | RAB9A (0.49) | ALDH1A1MEN1KMT2APOLBESR1 | |
| SCHEMBL8267185 | 0.73 | NPC1 (0.53) | ALDH1A1MEN1KMT2APOLBESR1 | |
| SCHEMBL27617928 | 0.72 | MAPT (0.59) | ALDH1A1KMT2AMAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |